CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028454
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 
Protein Synonyms/Alias
 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, isoform CRA_c 
Gene Name
 Ywhab 
Gene Synonyms/Alias
 mCG_5429 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
11DKSELVQKAKLAEQAubiquitination[1]
13SELVQKAKLAEQAERubiquitination[1]
29DDMAAAMKAVTEQGHubiquitination[1]
51NLLSVAYKNVVGARRubiquitination[1]
70VISSIEQKTERNEKKubiquitination[1]
140EVASGENKQTTVSNSubiquitination[1]
159QEAFEISKKEMQPTHubiquitination[1]
160EAFEISKKEMQPTHPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Monooxygenase; Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 246 AA 
Protein Sequence
MTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY KNVVGARRSS 60
WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICNDVL ELLDKYLILN ATQAESKVFY 120
LKMKGDYFRY LSEVASGENK QTTVSNSQQA YQEAFEISKK EMQPTHPIRL GLALNFSVFY 180
YEILNSPEKA CSLAKTAFDE AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD 240
AGEGEN 246 
Gene Ontology
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0017053; C:transcriptional repressor complex; IEA:Compara.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0019904; F:protein domain specific binding; IDA:MGI.
 GO:0003714; F:transcription corepressor activity; IEA:Compara.
 GO:0051220; P:cytoplasmic sequestering of protein; IEA:Compara.
 GO:0035308; P:negative regulation of protein dephosphorylation; IEA:Compara.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0043085; P:positive regulation of catalytic activity; IEA:Compara.
 GO:0051291; P:protein heterooligomerization; IEA:Compara.
 GO:0006605; P:protein targeting; IDA:MGI. 
Interpro
 IPR000308; 14-3-3.
 IPR023409; 14-3-3_CS.
 IPR023410; 14-3-3_domain. 
Pfam
 PF00244; 14-3-3 
SMART
 SM00101; 14_3_3 
PROSITE
 PS00796; 1433_1
 PS00797; 1433_2 
PRINTS
 PR00305; 1433ZETA.