CPLM-036569

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-036569

UniProt Accession

Genbank Protein ID

HQ206066; HQ206067; HQ206068; HQ206069; HQ206070; HQ206071; HQ206072; HQ206073; HQ206074; HQ206075; HQ206076; HQ206077; HQ206078; HQ206079; HQ206080; HQ206081; HQ206082; HQ206083; HQ206084; HQ206085; HQ206086; HQ206087; HQ206088; HQ206089; HQ206090; HQ206091; HQ206092; HQ206093; HQ206094; HQ206095; HQ206096; HQ206097; HQ206098; HQ206100; HQ206101; HQ206102; HQ206103; HQ206104; HQ206105; CH471083

Genbank Nucleotide ID

ADP91974.1; ADP91975.1; ADP91976.1; ADP91977.1; ADP91978.1; ADP91979.1; ADP91980.1; ADP91981.1; ADP91982.1; ADP91983.1; ADP91984.1; ADP91985.1; ADP91986.1; ADP91987.1; ADP91988.1; ADP91989.1; ADP91990.1; ADP91991.1; ADP91992.1; ADP91993.1; ADP91994.1; ADP91995.1; ADP91996.1; ADP91997.1; ADP91998.1; ADP91999.1; ADP92000.1; ADP92001.1; ADP92002.1; ADP92003.1; ADP92004.1; ADP92005.1; ADP92006.1; ADP92008.1; ADP92009.1; ADP92010.1; ADP92011.1; ADP92012.1; ADP92013.1; EAW54173.1

Protein Name

Mitochondrial transcription factor A

Protein Synonyms/Alias

Transcription factor A, mitochondrial, isoform CRA_c

Gene Name

TFAM

Gene Synonyms/Alias

hCG_40210

Created Date

July 27, 2013

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Lysine Modification

Position	Peptide	Type	References
52	VLASCPKKPVSSYLR	ubiquitination	[1]
62	SSYLRFSKEQLPIFK	ubiquitination	[1]
118	KEEISRFKEQLTPSQ	ubiquitination	[1, 2]

Reference

[1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
Chen Z, Zhou Y, Song J, Zhang Z.
Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
[2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]

Functional Description

Sequence Annotation

Keyword

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

246 AA

Protein Sequence

MAFLRSMWGV LSALGRSGAE LCTGCGSRLR SPFSFVYLPR WFSSVLASCP KKPVSSYLRF 60
SKEQLPIFKA QNPDAKTTEL IRRIAQRWRE LPDSKKKIYQ DAYRAEWQVY KEEISRFKEQ 120
LTPSQIMSLE KEIMDKHLKR KAMTKKKELT LLGKPKRPRS AYNVYVAERF QEAKGDSPQE 180
KLKTVKENWK NLSDSEKELY IQHAKEDETR YHNEMKSWEE QMIEVGRKDL LRRTIKKQRK 240
YGAEEC 246

Gene Ontology

GO:0005739; C:mitochondrion; IDA:HPA.
GO:0003677; F:DNA binding; IEA:Compara.
GO:0033108; P:mitochondrial respiratory chain complex assembly; IEA:Compara.

Interpro

IPR009071; HMG_box_dom.

Pfam

PF09011; DUF1898
PF00505; HMG_box

SMART

SM00398; HMG

PROSITE

PS50118; HMG_BOX_2

PRINTS