UniProt Accession

 MDHC1_ARATH; P93819 

Genbank Protein ID

 AC000104; CP002684; AY050374; AY065134; AY081563; AY133655; AY088023 

Genbank Nucleotide ID

 AAB70434.1; AEE27694.1; AAK91392.1; AAL38310.1; AAM10125.1; AAM91485.1; AAM65569.1 

Protein Name

 Malate dehydrogenase, cytoplasmic 1 

Protein Synonyms/Alias

  

Gene Name

 At1g04410; F19P19.13 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Arabidopsis thaliana (Mouse-ear cress) 

NCBI Taxa ID

 3702 

Lysine Modification

Position	Peptide	Type	References
3	*****MAKEPVRVLV	acetylation	[1]

Reference

 [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.
 Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.
 Plant Physiol. 2011 Apr;155(4):1779-90. [PMID: 21311031] 

Functional Description

  

Sequence Annotation

 NP_BIND 12 18 NAD (By similarity).
 NP_BIND 130 132 NAD (By similarity).
 ACT_SITE 188 188 Proton acceptor (By similarity).
 BINDING 93 93 Substrate (By similarity).
 BINDING 99 99 Substrate (By similarity).
 BINDING 106 106 NAD (By similarity).
 BINDING 113 113 NAD (By similarity).
 BINDING 132 132 Substrate (By similarity).
 BINDING 163 163 Substrate (By similarity).
 MOD_RES 204 204 Phosphoserine.
 MOD_RES 205 205 Phosphoserine.
 CROSSLNK 119 119 Glycyl lysine isopeptide (Lys-Gly)  

Keyword

 Complete proteome; Cytoplasm; Isopeptide bond; NAD; Oxidoreductase; Phosphoprotein; Reference proteome; Tricarboxylic acid cycle; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 332 AA 

Protein Sequence

Gene Ontology

 GO:0048046; C:apoplast; IDA:TAIR.
 GO:0009570; C:chloroplast stroma; IDA:TAIR.
 GO:0005634; C:nucleus; IDA:TAIR.
 GO:0005886; C:plasma membrane; IDA:TAIR.
 GO:0009506; C:plasmodesma; IDA:TAIR.
 GO:0005774; C:vacuolar membrane; IDA:TAIR.
 GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.
 GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
 GO:0006108; P:malate metabolic process; IEA:InterPro.
 GO:0046686; P:response to cadmium ion; IEP:TAIR.
 GO:0009651; P:response to salt stress; IEP:TAIR.
 GO:0010043; P:response to zinc ion; IEP:TAIR.
 GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. 

Interpro

 IPR001557; L-lactate/malate_DH.
 IPR022383; Lactate/malate_DH_C.
 IPR001236; Lactate/malate_DH_N.
 IPR015955; Lactate_DH/Glyco_Ohase_4_C.
 IPR001252; Malate_DH_AS.
 IPR011274; Malate_DH_NAD-dep_euk.
 IPR010945; Malate_DH_type2.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF02866; Ldh_1_C
 PF00056; Ldh_1_N 

SMART

  

PROSITE

 PS00068; MDH 

PRINTS