CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042463
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Caspase-9 subunit p35 
Protein Synonyms/Alias
  
Gene Name
 CASP9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
176VANAVSVKGIYKQMPubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protease; Reference proteome; Thiol protease; Zymogen. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 198 AA 
Protein Sequence
XCGHCLIINN VNFCRESGLR TRTGSNIDCE KLRRRFSSLH FMVEVKGDLT AKKMVLALLE 60
LAQQDHGALD CCVVVILSHG CQASHLQFPG AVYGTDGCPV SVEKIVNIFN GTSCPSLGGK 120
PKLFFIQACG GGFVSWRDPK SGSWYVETLD DIFEQWAHSE DLQSLLLRVA NAVSVKGIYK 180
QMPGCFNFLR KKLFFKTS 198 
Gene Ontology
 GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
 GO:0006915; P:apoptotic process; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 
Interpro
 IPR011600; Pept_C14_cat.
 IPR001309; Pept_C14_ICE_p20.
 IPR016129; Pept_C14_ICE_p20_AS.
 IPR002138; Pept_C14_p10.
 IPR002398; Pept_C14_p45.
 IPR015917; Pept_C14_p45_core. 
Pfam
 PF00656; Peptidase_C14 
SMART
 SM00115; CASc 
PROSITE
 PS01122; CASPASE_CYS
 PS01121; CASPASE_HIS
 PS50207; CASPASE_P10
 PS50208; CASPASE_P20 
PRINTS
 PR00376; IL1BCENZYME.