CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022205
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DnaJ homolog subfamily C member 11 
Protein Synonyms/Alias
  
Gene Name
 DNAJC11 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
31EASSEELKAAYRRLCubiquitination[1, 2]
83AIYDIYGKRGLEMEGubiquitination[1, 2, 3, 4]
126LQQRTNPKGTISVGVubiquitination[1]
226QGPLFGLKLFRNLTPubiquitination[5]
264VLARNLDKNTVGYLQubiquitination[1, 2, 3, 4]
409AMHRLIIKPYLRAQKubiquitination[2, 3, 4]
434AATDVLQKKQEAESAubiquitination[2]
435ATDVLQKKQEAESAVubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [5] Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
 Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.
 J Biol Chem. 2011 Dec 2;286(48):41530-8. [PMID: 21987572
Functional Description
  
Sequence Annotation
 DOMAIN 14 82 J.  
Keyword
 Alternative splicing; Chaperone; Coiled coil; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 559 AA 
Protein Sequence
MATALSEEEL DNEDYYSLLN VRREASSEEL KAAYRRLCML YHPDKHRDPE LKSQAERLFN 60
LVHQAYEVLS DPQTRAIYDI YGKRGLEMEG WEVVERRRTP AEIREEFERL QREREERRLQ 120
QRTNPKGTIS VGVDATDLFD RYDEEYEDVS GSSFPQIEIN KMHISQSIEA PLTATDTAIL 180
SGSLSTQNGN GGGSINFALR RVTSAKGWGE LEFGAGDLQG PLFGLKLFRN LTPRCFVTTN 240
CALQFSSRGI RPGLTTVLAR NLDKNTVGYL QWRWGIQSAM NTSIVRDTKT SHFTVALQLG 300
IPHSFALISY QHKFQDDDQT RVKGSLKAGF FGTVVEYGAE RKISRHSVLG AAVSVGVPQG 360
VSLKVKLNRA SQTYFFPIHL TDQLLPSAMF YATVGPLVVY FAMHRLIIKP YLRAQKEKEL 420
EKQRESAATD VLQKKQEAES AVRLMQESVR RIIEAEESRM GLIIVNAWYG KFVNDKSRKS 480
EKVKVIDVTV PLQCLVKDSK LILTEASKAG LPGFYDPCVG EEKNLKVLYQ FRGVLHQVMV 540
LDSEALRIPK QSHRIDTDG 559 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara. 
Interpro
 IPR024586; DnaJ-like_C11_C.
 IPR001623; DnaJ_domain.
 IPR018253; DnaJ_domain_CS. 
Pfam
 PF00226; DnaJ
 PF11875; DUF3395 
SMART
 SM00271; DnaJ 
PROSITE
 PS00636; DNAJ_1
 PS50076; DNAJ_2 
PRINTS
 PR00625; JDOMAIN.