UniProt Accession

 CANB1_RAT; P63100; P06705; P15117; Q08044 

Genbank Protein ID

 L03554; D14568; D14425; BC088855 

Genbank Nucleotide ID

 AAA40854.1; BAA03422.1; BAA03318.1; AAH88855.1 

Protein Name

 Calcineurin subunit B type 1 

Protein Synonyms/Alias

 Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 3 regulatory subunit B alpha isoform 1 

Gene Name

 Ppp3r1 

Gene Synonyms/Alias

 Cna2; Cnb 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
85	GVSQFSVKGDKEQKL	ubiquitination	[1]
125	MMVGNNLKDTQLQQI	acetylation	[2]
125	MMVGNNLKDTQLQQI	ubiquitination	[1]
135	QLQQIVDKTIINADK	acetylation	[2]
142	KTIINADKDGDGRIS	acetylation	[2]

Reference

 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. 

Sequence Annotation

 DOMAIN 18 51 EF-hand 1.
 DOMAIN 50 85 EF-hand 2.
 DOMAIN 87 122 EF-hand 3.
 DOMAIN 128 163 EF-hand 4.
 MOD_RES 106 106 Phosphotyrosine (By similarity).
 LIPID 2 2 N-myristoyl glycine.  

Keyword

 Alternative splicing; Calcium; Complete proteome; Lipoprotein; Metal-binding; Myristate; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 170 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004721; F:phosphoprotein phosphatase activity; IDA:RGD.
 GO:0006470; P:protein dephosphorylation; IDA:RGD. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 

Pfam

 PF13499; EF_hand_5
 PF00036; efhand 

SMART

 SM00054; EFh 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS