CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017255
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Meiotic nuclear division protein 1 homolog 
Protein Synonyms/Alias
  
Gene Name
 Mnd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
30TKDVFQLKDLEKLAPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. 
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; DNA recombination; DNA-binding; Meiosis; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 205 AA 
Protein Sequence
MSKKRGLSGE EKRTRMMEIF FETKDVFQLK DLEKLAPKEK GITAMSVKEV LQSLVDDGMV 60
DCERIGTSNY YWAFPSKALH ARKRKLEALN SQLSEGSQKH ADLQKSIEKA RVGRQETEER 120
AMLAKELSSF RDQRQQLKAE VEKYRECDPQ VVEEIREANK VAKEAANRWT DNIFAIKSWA 180
KRKFGFEESK IDKNFGIPED FDYID 205 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
 GO:0007126; P:meiosis; IEA:UniProtKB-KW. 
Interpro
 IPR005647; Mnd1. 
Pfam
 PF03962; Mnd1 
SMART
  
PROSITE
  
PRINTS