CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026605
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MFLJ00316 protein 
Protein Synonyms/Alias
  
Gene Name
 Gbp7 
Gene Synonyms/Alias
 Gbp6; mFLJ00316 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
384DENQQFQKNLVVTIEubiquitination[1]
513ELLRQKQKELQQVMEubiquitination[1]
527EAQERSYKENVAQLHubiquitination[1]
568DMLNEGFKRKCEAMDubiquitination[1]
616SVVPGSGKYFGLGLKubiquitination[1, 2]
623KYFGLGLKILSSQMNubiquitination[1, 2]
637NQTQNSDKVRKL***ubiquitination[1, 2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.
 Mathew R, Seiler MP, Scanlon ST, Mao AP, Constantinides MG, Bertozzi-Villa C, Singer JD, Bendelac A.
 Nature. 2012 Nov 22;491(7425):618-21. [PMID: 23086144] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 641 AA 
Protein Sequence
LVTMASGPNM EAPVCLVENE NEELRVNSKA INILERITQP VVVVAIVGLY RTGKSYLMNR 60
LAGQNHGFNL GTTVRSETKG IWMWCVPHPS KPKFTLVLLD TEGLGDVEKG DPKNDSWIFA 120
LAVLLSSTFV YNSMSTINHQ ALEQLHYVTE LTERIRAKST SRSEEVDDSD EFVSFFPDFI 180
WTVRDFVLEL KLEGRVITAD EYLENALKLI PGMSIKAQKA NLPRECIRHF FPRRKCFVFD 240
RPTKDKELLV HVEEMPEDQL DHSFQVQSKE FCSYIFSNSK AKTLKEGIVV NGNRLATLVT 300
TYVDAINSGD VPCLENAVTT LAQRENSIAV QKAADHYSEQ MAQRMRLPTD TLQELLTVHT 360
ACEKEAIAVF MEHSFKDENQ QFQKNLVVTI EEKKEDFLRQ NEAASLSHCQ AELDKLSESL 420
RESISRGVFS VPGGHRLYLE ARKKVEQDYE RVPRKGVKAN HVLQSFLQSQ ISIEDSIMQS 480
DKALTDGQKA MEAERAQKEA AEKEQELLRQ KQKELQQVME AQERSYKENV AQLHEKMETE 540
RKNILREQEV KLEHKLKIQK DMLNEGFKRK CEAMDLEISQ LQKEIQLNKE KNSSLGAKIL 600
DGFGDVLISV VPGSGKYFGL GLKILSSQMN QTQNSDKVRK L 641 
Gene Ontology
 GO:0031410; C:cytoplasmic vesicle; IDA:MGI.
 GO:0020005; C:symbiont-containing vacuole membrane; IDA:MGI.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0051856; P:adhesion to symbiont; IDA:MGI.
 GO:0071346; P:cellular response to interferon-gamma; IDA:MGI.
 GO:0050830; P:defense response to Gram-positive bacterium; IDA:MGI.
 GO:0042832; P:defense response to protozoan; IDA:MGI.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR003191; Guanylate-bd_C.
 IPR015894; Guanylate-bd_N.
 IPR027417; P-loop_NTPase. 
Pfam
 PF02263; GBP
 PF02841; GBP_C 
SMART
  
PROSITE
  
PRINTS