CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027624
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
527PGRDTTKKENFRPISacetylation[1]
541SLMNIDAKILNKILAacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 REGION 18 19 Sulfate 1 binding.
 REGION 21 22 Sulfate 2 binding.
 BINDING 23 23 Sulfate 1.
 BINDING 43 43 Sulfate 3.
 BINDING 45 45 Sulfate 1.
 BINDING 45 45 Sulfate 4.
 BINDING 72 72 Sulfate 4; via amide nitrogen.
 BINDING 115 115 Sulfate 4.
 BINDING 145 145 Sulfate 3.
 BINDING 155 155 Sulfate 5.  
Keyword
 3D-structure. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1275 AA 
Protein Sequence
MTGSNSHITI LTLNINGLNS AIKRHRLASW IKSQDPSVCC IQETHLTCRD THRLKIKGWR 60
KIYQANGKQK KAGVAILVSD KTDFKPTKIK RDKEGHYIMV KGSIQQEELT ILNIYAPNTG 120
APRFIKQVLS DLQRDLDSHT LIMGDFNTPL STLDRSTRQK VNKDTQELNS ALHQADLIDI 180
YRTLHPKSTE YTFFSAPHHT YSKIDHIVGS KALLSKCKRT EIITNYLSDH SAIKLELRIK 240
NLTQSHSTTW KLNNLLLNDY WVHNEMKAEI KMFFETNENN DTTYQNLWDA FKAVCRGKFI 300
ALNAYKRKQE RSKIDTLTSQ LKELEKQEQT HSKASRRQEI TKIRAELKEI ETQKTLQKIN 360
ESRSWFFERI NKIDRPLARL IKKKREKNQI DTIKNDKGDI TTDPTEIQTT IREYYKHLYA 420
NKLENLEEMD TFLDTYTLPR LNQEEVESLN RPITGSEIVA IINSLPTKKS PGPDGFTAEF 480
YQRYKEELVP FLLKLFQSIE KEGILPNSFY EASIILIPKP GRDTTKKENF RPISLMNIDA 540
KILNKILANR IQQHIKKLIH HDQVGFIPGM QGWFNIRKSI NVIQHINRAK DKNHMIISID 600
AEKAFDKIQQ PFMLKTLNKL GIDGTYFKII RAIYDKPTAN IILNGQKLEA FPLKTGTRQG 660
CPLSPLLFNI VLEVLARAIR QEKEIKGIQL GKEEVKLSLF ADDMIVYLEN PIVSAQNLLK 720
LISNFSKVSG YKINVQKSQA FLYTNNRQTE SQIMGELPFT IASKRIKYLG IQLTRDVKDL 780
FKENYKPLLK EIKEDTNKWK NIPCSWVGRI NIVKMAILPK VIYRFNAIPI KLPMTFFTEL 840
EKTTLKFIWN QKRARIAKSI LSQKNKAGGI TLPDFKLYYK ATVTKTAWYW YQNRDIDQWN 900
RTEPSEIMPH IYNYLIFDKP EKNKQWGKDS LFNKWCWENW LAICTKLKLD PFLTPYTKIN 960
SRWIKDLNVR PKTIKTLEEN LGITIQDIGV GKDFMSKTPK AMATKVKIDK WDLIKLKSFC 1020
TAKETTIRVN RQPTTWEKIF ATYSSDKGLI SRIYNELKQI YKKKTNNPIK KWAKDMNRHF 1080
SKEDIYAAKK HMKKCSSSLA IREMQIKTTM RYHLTPVRMA IIKKSGNNRC WRGCGEIGTL 1140
LHCWWDCKLV QPLWKSVWRF LRDLELEIPF DPAIPLLGIY PNEYKSCCYK DTCTRMFIVA 1200
LFTIAKTWNQ LKCPTMIDWI KKMWHIYTME YYAAIKNDEF ISFVGTWMKL ETIILSKLSQ 1260
EQKTKHRIFS LIGGN 1275 
Gene Ontology
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0003964; F:RNA-directed DNA polymerase activity; IEA:InterPro.
 GO:0006278; P:RNA-dependent DNA replication; IEA:InterPro. 
Interpro
 IPR013544; DUF1725.
 IPR005135; Endo/exonuclease/phosphatase.
 IPR000477; RVT. 
Pfam
 PF08333; DUF1725
 PF03372; Exo_endo_phos
 PF00078; RVT_1 
SMART
  
PROSITE
 PS50878; RT_POL 
PRINTS