CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011267
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein TRI1 
Protein Synonyms/Alias
  
Gene Name
 TRI1 
Gene Synonyms/Alias
 YMR233W; YM9959.15 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
68NPRVLIPKNDLISRDacetylation[1]
201FNPDEIVKHEEEQKQsumoylation[2]
215QTPEKEIKLENESLPsumoylation[2]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Topoisomerase I-dependent viability loss in saccharomyces cerevisiae mutants defective in both SUMO conjugation and DNA repair.
 Chen XL, Silver HR, Xiong L, Belichenko I, Adegite C, Johnson ES.
 Genetics. 2007 Sep;177(1):17-30. [PMID: 17603101
Functional Description
 May be involved in transcription regulation (By similarity). 
Sequence Annotation
 MOD_RES 113 113 Phosphoserine.
 MOD_RES 225 225 Phosphoserine.
 CROSSLNK 201 201 Glycyl lysine isopeptide (Lys-Gly)
 CROSSLNK 215 215 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Complete proteome; Cytoplasm; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 226 AA 
Protein Sequence
MADINKYIPM VDAILSVSNP DEISPKRVRK ALQILYSVNL DSQRKLINEL ILERFGDIQE 60
NPRVLIPKND LISRDQELSL RLQKEEERPL RSTRKRKGKS ESKSKRKKKK NDSPDSNSIS 120
VRKVLLSAPL QKFLGSEELP RTQVVKMIWQ YIKEHDLQNP KDRREILCDE KMEPIFGKKM 180
TMFSMNKLLT KHLFNPDEIV KHEEEQKQTP EKEIKLENES LPNLSG 226 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005730; C:nucleolus; IDA:SGD.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR014876; DEK_C.
 IPR009057; Homeodomain-like.
 IPR019835; SWIB_domain.
 IPR003121; SWIB_MDM2_domain. 
Pfam
 PF08766; DEK_C
 PF02201; SWIB 
SMART
 SM00151; SWIB 
PROSITE
  
PRINTS