UniProt Accession

 E9PNR6_HUMAN; E9PNR6 

Genbank Protein ID

 AC115088 

Genbank Nucleotide ID

  

Protein Name

 Rho GTPase-activating protein 1 

Protein Synonyms/Alias

  

Gene Name

 ARHGAP1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
48	FPKSDDSKSSSPELV	ubiquitination	[1]
59	PELVTHLKWDDPYYD	ubiquitination	[2]
80	VEVAGDDKYGRKIIV	ubiquitination	[1, 2, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 192 AA 

Protein Sequence

Gene Ontology

 GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0001726; C:ruffle; IEA:Compara.
 GO:0030675; F:Rac GTPase activator activity; IEA:Compara. 

Interpro

 IPR001251; CRAL-TRIO_dom. 

Pfam

  

SMART

 SM00516; SEC14 

PROSITE

 PS50191; CRAL_TRIO 

PRINTS