CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041575
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Synapsin-2 
Protein Synonyms/Alias
  
Gene Name
 Syn2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
107EPHTDWAKCFRGKKIacetylation[1]
113AKCFRGKKILGDYDIubiquitination[2]
222FKTLGGEKFPLIEQTacetylation[1]
420QPQSGTLKEPDSSKTubiquitination[2]
556ETIRSLRKSFASLFSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 564 AA 
Protein Sequence
MTDLQRPEPQ QPPPAPGPGT ATASAATSAA SPGPERRPPP AQAPAPQPAP QPAPTPSVGS 60
SFFSSLSQAV KQTAASAGLV DAPAPSAASR KAKVLLVVDE PHTDWAKCFR GKKILGDYDI 120
KVEQAEFSEL NLVAHADGTY AVDMQVLRNG TKVVRSFRPD FVLIRQHAFG MAENEDFRHL 180
VIGMQYAGLP SINSLESIYN FCDKPWVFAQ MVAIFKTLGG EKFPLIEQTY YPNHREMLTL 240
PTFPVVVKIG HAHSGMGKVK VENHYDFQDI ASVVALTQTY ATAEPFIDAK YDIRVQKIGN 300
NYKAYMRTSI SGNWKTNTGS AMLEQIAMSD RYKLWVDACS EMFGGLDICA VKAVHGKDGK 360
DYIFEVMDCS MPLIGEHQVE DRQLITDLVI SKMNQLLSRT PALSPQRPLT TQQPQSGTLK 420
EPDSSKTPPQ RPAPQGGPGQ PQGMQPPGKV LPPRRLPSGP SLPPSSSSSS SSSSSSSAPQ 480
RPGGPTTTHG DASSSSNSLA EAQAPQAAPP QKPQPHPQLN KSQSLTNAFS FSESSFFRSS 540
ANEDEAKAET IRSLRKSFAS LFSD 564 
Gene Ontology
 GO:0030672; C:synaptic vesicle membrane; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC.
 GO:0007269; P:neurotransmitter secretion; IEA:Compara. 
Interpro
 IPR013815; ATP_grasp_subdomain_1.
 IPR013816; ATP_grasp_subdomain_2.
 IPR016185; PreATP-grasp_dom.
 IPR001359; Synapsin.
 IPR020898; Synapsin_ATP-bd_dom.
 IPR019735; Synapsin_CS.
 IPR020897; Synapsin_pre-ATP-grasp_dom. 
Pfam
 PF02078; Synapsin
 PF02750; Synapsin_C 
SMART
  
PROSITE
 PS00416; SYNAPSIN_2 
PRINTS
 PR01368; SYNAPSIN.