UniProt Accession

 E9PM62_HUMAN; E9PM62 

Genbank Protein ID

 AL157407; AL513284 

Genbank Nucleotide ID

  

Protein Name

 Protein wntless homolog 

Protein Synonyms/Alias

  

Gene Name

 WLS 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
16	RKNHHKTKWFVPWGP	ubiquitination	[1, 2]
28	WGPNHCDKIRDIEEA	ubiquitination	[1, 2, 3]
172	NVGIGEIKDIRLVGI	ubiquitination	[2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 222 AA 

Protein Sequence

Gene Ontology

 GO:0031410; C:cytoplasmic vesicle; IEA:Compara.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0009948; P:anterior/posterior axis specification; IEA:Compara.
 GO:0001707; P:mesoderm formation; IEA:Compara.
 GO:0016055; P:Wnt receptor signaling pathway; IEA:Compara. 

Interpro

 IPR009551; Wntless. 

Pfam

  

SMART

  

PROSITE

  

PRINTS