UniProt Accession

 G3XA48_MOUSE; G3XA48 

Genbank Protein ID

 AC124732; CH466588 

Genbank Nucleotide ID

 EDL32280.1 

Protein Name

 Isopentenyl-diphosphate Delta-isomerase 1 

Protein Synonyms/Alias

 Isopentenyl-diphosphate delta isomerase 

Gene Name

 Idi1 

Gene Synonyms/Alias

 mCG_4413 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
93	KIGADTKKNCHLNEN	ubiquitination	[1]
103	HLNENIDKGLLHRAF	acetylation	[2]
169	RAAKRRLKAELGIPL	ubiquitination	[1]
225	NPDPNEIKSYCYVSK	acetylation	[2]
225	NPDPNEIKSYCYVSK	ubiquitination	[1]
232	KSYCYVSKEEVREIL	acetylation	[2, 3]
248	KAASGEIKLTPWFKI	ubiquitination	[1]
279	SPFVDHEKIHRL***	acetylation	[2]
279	SPFVDHEKIHRL***	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Isomerase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 283 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005777; C:peroxisome; IEA:Compara.
 GO:0016787; F:hydrolase activity; IEA:InterPro.
 GO:0004452; F:isopentenyl-diphosphate delta-isomerase activity; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:Compara.
 GO:0030145; F:manganese ion binding; IEA:Compara.
 GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. 

Interpro

 IPR011876; IsopentenylPP_isomerase_typ1.
 IPR000086; NUDIX_hydrolase_dom.
 IPR015797; NUDIX_hydrolase_dom-like. 

Pfam

 PF00293; NUDIX 

SMART

  

PROSITE

 PS51462; NUDIX 

PRINTS