CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032775
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutamyl-tRNA synthetase, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_049140 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
476FSRLCFVKTLLSKRKacetylation[1, 2]
686DHLITVDKIDQEEENacetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Ligase; Nucleotide-binding; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 786 AA 
Protein Sequence
MLRVRYSPQH PPLVTLCVSA LLERGLAACV PDNSLQDSLL SVQKTESGSE EVFTDIAAAK 60
LLCTLSSKTR LLYPAAAPAP SFADASETAC IDTMLSLATS LQVSSLSPKQ LGSLSSHLQL 120
RTFLCGFHLS LADLAVYTQL RRHANNEQQG GAPPQGWKDK FVHVSRWYAF IHGQPQISNV 180
VAVALRKAGA NAKGAEASKN EGKKREGRAN SSGASSPPSA DKRAAAAQAS YEGKLEGAVQ 240
GKVVTRFPPE PSGYLHIGHA KAALLNSYFA QKYNGKMLFR FDDTNPAKEN DEFESSIAED 300
LRLLNVEWAA ISHTSDYFEQ MQSLCERLIK EGKFYVDDTP TELMREQRAE GIESCRRNVP 360
VEESLQRWRE MLKGSAEGQK CCVRAKIDMQ SKNKCMRDPV MYRCVADCLH HRHGDKFKAY 420
PTYDFACPVV DSIEGVTHAL RTNEYADRIP QYQWVQQAAG LPPVHIYEFS RLCFVKTLLS 480
KRKLKQFVDS GLVEGWDDPR MPTVRGIRRR GLQVEALLEF ILEQGPSKAG NLMEWDKLWT 540
KNKQIIDPIV PRFMAVGKDA VPVCIKGAPE TVESKKRRMH AKNESLGEAD LLLFNKVFID 600
RDDAALCADG EEVTLMHWGN CIFDKVVKTA SGEISEIQAT LHLEGDFRKT KKKLHWLANL 660
GGVASAPAQN TELVLREYDH LITVDKIDQE EENWEKFINR ETRFDTPAVG DPLLKQLKEG 720
EARFSEVRKE RQFRQSGLVT RRGRCLSRGM NFVGKRFKVV SSVDRWNLRV SSEGRQLPRH 780
AAVGKE 786 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004818; F:glutamate-tRNA ligase activity; IEA:InterPro.
 GO:0004819; F:glutamine-tRNA ligase activity; IEA:EC.
 GO:0006424; P:glutamyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR001412; aa-tRNA-synth_I_CS.
 IPR004526; Glu-tRNA-synth_Ib_arc/euk.
 IPR000924; Glu/Gln-tRNA-synth_Ib.
 IPR020061; Glu/Gln-tRNA-synth_Ib_a-bdl.
 IPR020058; Glu/Gln-tRNA-synth_Ib_cat-dom.
 IPR020059; Glu/Gln-tRNA-synth_Ib_codon-bd.
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR020056; Rbsml_L25/Gln-tRNA_synth_b-brl.
 IPR011035; Ribosomal_L25/Gln-tRNA_synth.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF00749; tRNA-synt_1c
 PF03950; tRNA-synt_1c_C 
SMART
  
PROSITE
 PS00178; AA_TRNA_LIGASE_I
 PS50405; GST_CTER 
PRINTS
 PR00987; TRNASYNTHGLU.