CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030984
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription factor Dp-1 
Protein Synonyms/Alias
 cDNA FLJ50802, highly similar to Transcription factor Dp-1 
Gene Name
 TFDP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
27GLRHFSMKVCEKVQRubiquitination[1]
91MNIISKEKKEIKWIGubiquitination[1]
92NIISKEKKEIKWIGLubiquitination[1]
95SKEKKEIKWIGLPTNubiquitination[1, 2]
122QRRLERIKQKQSQLQubiquitination[1]
124RLERIKQKQSQLQELubiquitination[1]
139ILQQIAFKNLVQRNRubiquitination[1]
225SCSAEDLKMARSLVPubiquitination[1, 3, 4, 5]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [5] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 311 AA 
Protein Sequence
MSTLPSKWKR NRKGEKNGKG LRHFSMKVCE KVQRKGTTSY NEVADELVAE FSAADNHILP 60
NESAYDQKNI RRRVYDALNV LMAMNIISKE KKEIKWIGLP TNSAQECQNL EVERQRRLER 120
IKQKQSQLQE LILQQIAFKN LVQRNRHAEQ QASRPPPPNS VIHLPFIIVN TSKKTVIDCS 180
ISNDKFEYLF NFDNTFEIHD DIEVLKRMGM ACGLESGSCS AEDLKMARSL VPKALEPYVT 240
EMAQGTVGGV FITTAGSTSN GTSDLTNGAD GMLATSSNGS QYSGSRVETP VSYVGEDDEE 300
DDDFNENDED D 311 
Gene Ontology
 GO:0005667; C:transcription factor complex; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR003316; E2F_TDP.
 IPR014889; Transc_factor_DP_C.
 IPR016556; Transcription_factor_DP_subgr.
 IPR015648; Transcrpt_fac_DP.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF08781; DP
 PF02319; E2F_TDP 
SMART
  
PROSITE
  
PRINTS