UniProt Accession

 Q5T7F5_HUMAN; Q5T7F5; E9PFI1 

Genbank Protein ID

 AL353597 

Genbank Nucleotide ID

  

Protein Name

 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 

Protein Synonyms/Alias

  

Gene Name

 FTSJD2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
93	MYNSVSQKLMAKMGF	ubiquitination	[1]
97	VSQKLMAKMGFREGE	ubiquitination	[1]
108	REGEGLGKYSQGRKD	ubiquitination	[1]
114	GKYSQGRKDIVEASS	ubiquitination	[1]
123	IVEASSQKGRRGLGL	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 372 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0008168; F:methyltransferase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 

Interpro

 IPR000467; G_patch_dom.
 IPR002877; rRNA_MeTrfase_FtsJ_dom. 

Pfam

 PF01728; FtsJ
 PF01585; G-patch 

SMART

 SM00443; G_patch 

PROSITE

 PS50174; G_PATCH 

PRINTS