CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035176
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Ptprb 
Protein Synonyms/Alias
  
Gene Name
 Ptprb 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1714SKEYEDLKDVGRSQSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protein phosphatase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2000 AA 
Protein Sequence
MLSHGALLAL WIALSVLQTG VAEQVKCNFT VLESKVSSLS ASIQWRTFGS PCNFSLIYSS 60
DTSGPLWCHP ILIDNFTYGC DPKDLQAGTI YNFRIVSLDG EERSLVLQTD PLPPARLEVN 120
PERTTSTTLQ VRWTPSSGKV TWYEVQLFDQ NNQKIQEVQV QESATWSQYT FLNLTAGSSY 180
KIGITAVSGG KRSFPVYTNG STGPSPVEDI GISPNPNSLL ISWSRGPGNV EQFRLMLMDK 240
GAIVQDTNVD KRDTSYAFRG LTPGHLYNVT IVTMASGLQN SRWKLGRTAP MEVSNLKVTS 300
GGSLTSLNVK WQKPLGVIDS YSITLSHQGT VKESKTLPPR ATEIQFKDLV PGRFYQVTIR 360
CVSGELSAEK SAMGRTVPEK VSNLVSYNEI WMKSFAVNWT PPAGDWDHYR ILLFNDSLVL 420
LNTTVGKEET HFALEGLELI PGRQYEVEVI VESGNLRNSE RCQGRTVPLA VLQLRIKQAN 480
ETSLGITWRA PLGEWEKYTI SLMDRELFVI HKSLSKDAKE YTFTNLMPGR NYKATVTSMS 540
GDLKQSASIQ GRTVPAQVTD LEVSNQGMTS SLFTNWTKAL GDVEFYQVLL IHENVVVKNE 600
SVSSDSSWYS FRALRSGSLY SVVVTTVSGG IPSRQVVAEG RTVPSSVSGV TVNNSGRNDY 660
LSVSWLPAPG EVHHYVVTLS HDSKVVQSLI TAKFVSECSF SSLTPGRLYN VTITTKSGNY 720
ESHSFSEERT VPDKVQGISV SNSARSDYLK VSWVHATGDF DHYEVTIKNR DSFIQTKSIP 780
KSENECVFAR LVPGRLYSIT VTTKSGQYEA SEQGTGRTIP EPVKNLTLLN RSTEDLHVTW 840
SRANGDVDQY EVQLLFNDMK VFPPIYLVNT ATEYQFSALT PGRHYKILVL TISGDVQQPA 900
FIEGLTVPST VKNIHISANG ATDRLTVTWS PGGGDVDSYV VSAFRQDEKV ESHTLPKHGS 960
EHTFHRLEAG ATYRIAIVSV SGSLRNQIDV LGQTVPASVH GVVADNAYSS NSLTVSWQKA 1020
LGMAERYDIL LLSENGVLLS NTSEPATVKQ HKFEDLTPGK KYKMQILTVS GGLFSKEVET 1080
EGRTVPAAVT NLRITENSSR HLSFSWTASE GELSWYNIFL YNPDKTLQER AQVDPLVQSF 1140
SFQNLLQGRM YKMVIVTHSG ELSNESFIFG RTVPAAVNHL KGSNRNMTDS LWFSWSPASG 1200
DFDFYELILY NPNGTKKENW REKDVTEWRF QGLIPGRKYT LYVVTHSGDL SNKVTGEGRT 1260
APSPPSLLSF ADVANTSLAI TWKGPPDWTD YNDFELQWLP GDALTVFNPY SSKKSEGRIV 1320
NGLRPGRSYQ FSVKTVSGDS WKTYSKPISG SVRTKPDKIQ NLHCRPQNST AIACSWIPPD 1380
SDFDGYSIEC RKMDTQEIEF SRKLEKEKSL LNIMMLVPHR RYLVSIKVQS AGVTSEVVED 1440
STITMIDRPP PPPPHIRVNE KDVLISKSSI NFTVNCSWFS DTNGAVKYFA VVVREADSMD 1500
ELRPEQQHPL PSYLEYRHNA SIRVYQTNYF ASKCAESPDP DRSSKSFNIK LGGEMDSLGG 1560
KCDPSQQKFC DGPLKPHTAY RISIRAFTQL FDEGLKEFTK PLYSDTFFSM PITTESEPLF 1620
GVIEGVSAGL FLIGMLVALV AFFICRQKAS HSRERSSARL SIRRDRPLSV HLNLGQKGNR 1680
KTSCPIKINQ FEGHFMKLQA DSNYLLSKEY EDLKDVGRSQ SCDIALLPEN RGKNRYNNIL 1740
PYDASRVKLC NVDDDPCSDY INASYIPGNN FRREYIATQG PLPGTKDDFW KMAWEQNVHN 1800
IVMVTQCVEK GRVKCDHYWP ADQDPLYYGD LILQMVSESV LPEWTIREFK ICSEEQLDAH 1860
RLLRHFHYTV WPDHGVPETT QSLIQFVRTV RDYINRSPGA GPTVVHCSAG VGRTGTFVAL 1920
DRILQQLDSK DSVDIYGAVH DLRLHRVHMV QTECQYVYLH QCVRDVLRAR KLRNEQENPL 1980
FPIYENVNPE YHRGSFSKMH 2000 
Gene Ontology
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold.
 IPR000387; Tyr/Dual-sp_Pase.
 IPR016130; Tyr_Pase_AS.
 IPR000242; Tyr_Pase_rcpt/non-rcpt. 
Pfam
 PF00041; fn3
 PF00102; Y_phosphatase 
SMART
 SM00060; FN3
 SM00194; PTPc 
PROSITE
 PS50853; FN3
 PS00383; TYR_PHOSPHATASE_1
 PS50056; TYR_PHOSPHATASE_2
 PS50055; TYR_PHOSPHATASE_PTP 
PRINTS
 PR00700; PRTYPHPHTASE.