UniProt Accession

 ARSC_ECOLI; P0AB96; P37311; Q2M7G5 

Genbank Protein ID

 X80057; U00039; U00096; AP009048 

Genbank Nucleotide ID

 CAA56363.1; AAB18479.1; AAC76528.1; BAE77791.1 

Protein Name

 Arsenate reductase 

Protein Synonyms/Alias

 Arsenical pump modifier 

Gene Name

 arsC 

Gene Synonyms/Alias

 arsG; b3503; JW3470 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
61	SVRALLRKNVEPYEE	acetylation	[1]
75	ELGLAEDKFTDDRLI	acetylation	[1]
126	AQKGAFSKEDGEKVV	acetylation	[1]
131	FSKEDGEKVVDEAGK	acetylation	[1]
138	KVVDEAGKRLK****	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance (By similarity). 

Sequence Annotation

  

Keyword

 Arsenical resistance; Complete proteome; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 141 AA 

Protein Sequence

Gene Ontology

 GO:0008794; F:arsenate reductase (glutaredoxin) activity; IEA:EC.
 GO:0046685; P:response to arsenic-containing substance; IEA:UniProtKB-KW.
 GO:0006974; P:response to DNA damage stimulus; IEP:EcoliWiki. 

Interpro

 IPR006659; Arsenate_reductase.
 IPR006660; Arsenate_reductase-like.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF03960; ArsC 

SMART

  

PROSITE

 PS51353; ARSC 

PRINTS