CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018429
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 
Protein Synonyms/Alias
 BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM 
Gene Name
 gpmA 
Gene Synonyms/Alias
 STM0772 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
100GALQGLNKAETAEKYacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786
Functional Description
 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity). 
Sequence Annotation
 REGION 23 24 2-phospho-D-glycerate binding (By
 REGION 89 92 2-phospho-D-glycerate binding (By
 REGION 116 117 2-phospho-D-glycerate binding (By
 ACT_SITE 11 11 Tele-phosphohistidine intermediate (By
 ACT_SITE 184 184 By similarity.
 BINDING 17 17 2-phospho-D-glycerate (By similarity).
 BINDING 62 62 2-phospho-D-glycerate (By similarity).
 BINDING 100 100 2-phospho-D-glycerate (By similarity).
 BINDING 186 186 2-phospho-D-glycerate (By similarity).  
Keyword
 Complete proteome; Glycolysis; Isomerase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 250 AA 
Protein Sequence
MAVTKLVLVR HGESQWNKEN RFTGWYDVDL SEKGVSEAKA AGKLLKEEGF SFDFAYTSVL 60
KRAIHTLWNV LDELDQAWLP VEKSWKLNER HYGALQGLNK AETAEKYGDE QVKQWRRGFA 120
VTPPELTKDD ERYPGHDPRY AKLSEKELPL TESLALTIDR VIPYWNDTIL PRMKSGERVI 180
IAAHGNSLRA LVKYLDNMSE DEILELNIPT GVPLVYEFDE NFKPLKHYYL GNADEIAAKA 240
AAVANQGKAK 250 
Gene Ontology
 GO:0046538; F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; IEA:HAMAP.
 GO:0006096; P:glycolysis; IEA:HAMAP. 
Interpro
 IPR013078; His_Pase_superF_clade-1.
 IPR001345; PG/BPGM_mutase_AS.
 IPR005952; Phosphogly_mut1. 
Pfam
 PF00300; His_Phos_1 
SMART
 SM00855; PGAM 
PROSITE
 PS00175; PG_MUTASE 
PRINTS