| Tag | Content |
|---|
| CPLM ID | CPLM-016666 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | RAD50-interacting protein 1 |
Protein Synonyms/Alias | RAD50 interactor 1; RINT-1 |
Gene Name | Rint1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 69 | KEVGSDLKSLKTLGK | ubiquitination | [1] | | 502 | NLPTASRKLQFLELQ | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. May play a role in cell cycle checkpoint control. Essential for telomere length control (By similarity). |
Sequence Annotation | DOMAIN 220 792 RINT1/TIP20. |
Keyword | Alternative splicing; Cell cycle; Coiled coil; Complete proteome; Cytoplasm; Endoplasmic reticulum; ER-Golgi transport; Membrane; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 792 AA |
Protein Sequence | MLAADDIGEV PAAPCCPESG DETKNTDVKS DVNTAAPAGS EQLSQGGSDD ALLSYVSAFI 60
EKEVGSDLKS LKTLGKLIEQ MTESKVKLEE QVLTISSEIP KRIQSALKDA EESKQLLDEF 120
LEQEAPLFSS ISSHLLMAQP WMDDLGAMIT QMEEIERHLA YLKWVSQTEE LSDNIQQYLM 180
TNSVPEAASL LVTMTELDIQ LQESSCTHLL SFMRATVKFW HKILKDKLTS DFEEVLAQLH 240
WPFTSHTQSQ TVGGSRPAGT PELYSSLDTL FCQLLKLQAS DELLTEPKQL PEKYCLPASP 300
PVTLPIQVML APLQKRFRYH FRGSRQTNVM SKPEWYLAQV LMWIGNHTQF LDEKIQPILD 360
KVGSAVNARL EFSRGLVMLI LEKLASDIPC LLYDDSLFCH LVDEVLLFER ELHTVHGYPS 420
TFASCMHILS EETCFQRWLT VERKFALQKM DSMLSSEAAW VSQYKDISDV DEMKVPDCAE 480
VFMTLLLVIT DRYKNLPTAS RKLQFLELQK DLVDDFRIRL TQVMKEETRA ALGFRYCAIL 540
NAVNYISAVL ADWADNVFFL QLQQAALEVF AENNVLSKLQ LGQLASMESS VFDDMINLLE 600
RLKLDMLTRQ VDHVFREVKD SAKLYKKERW LSLPSQSEQA VMSLSSSACP LLLTLRDRLL 660
QLEQQLCFSL FRIFWQMLAE KLDLYIYQEI ILANHFNEGG AAQLQFDMTR NLFPLFSHYC 720
KRPENYFKHV KEACIILNLN IGSALLLKDV LQSVSEHIPA TAALNEVGVY KLAQQDVEIL 780
LNLRTNWPNT GK 792 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; ISS:HGNC. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0007049; P:cell cycle; IEA:UniProtKB-KW. GO:0031572; P:G2 DNA damage checkpoint; ISS:HGNC. GO:0015031; P:protein transport; IEA:UniProtKB-KW. GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |