CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039026
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Cdc23 
Protein Synonyms/Alias
  
Gene Name
 Cdc23 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
453LNQLVEAKKCYWRAYacetylation[1]
467YAVGDVEKMALVKLAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 597 AA 
Protein Sequence
MAANSSVVSV AAAATTVPGV STVADFSDLR EIKKQLLLIA GLTRERGLLH SSKWSAELAF 60
SLPALPLSEL QPPPPLTEED AQDVDAYTLA KAYFDVKEYD RAAHFLHGCN SKKAYFLYMY 120
SRYLSGEKKK DDETVDSLGP LEKGQVKNEA LRELRVELSR KHQARGLDGF GLYLYGVVLR 180
KLDLVKEAID VFVEATHVLP LHWGAWLELC NLITDKEMLK FLSLPDTWMK EFFLAHIYTE 240
LQLIEEALQK YQHLIDVGFS KSSYIVSQIA VAYHNIRDID KALSIFNELR KQDPYRIENM 300
DTFSNLLYVR SMKSELSYLA HNLCEIDKYR VETCCVIGNY YSLRSQHEKA ALYFQRALKL 360
NPRYLGAWTL MGHEYMEMKN TSAAIQAYRH AIEVNKRDYR AWYGLGQTYE ILKMPFYCLY 420
YYRRAHQLRP NDSRMLVALG ECYEKLNQLV EAKKCYWRAY AVGDVEKMAL VKLAKLHEQL 480
TESEQAAQCY IKYIQDIYSC GETVEHLEES TAFRYLAQYY FKCKLWDEAS TCAQKCCAFN 540
DTREEGKALL RQILQLRNQG ETPTSDTPGT FFLPASLSAN NTPTRRVSPL NLSSVTP 597 
Gene Ontology
 GO:0005680; C:anaphase-promoting complex; IEA:Compara.
 GO:0007080; P:mitotic metaphase plate congression; IEA:Compara.
 GO:0070979; P:protein K11-linked ubiquitination; IEA:Compara.
 GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IEA:Compara. 
Interpro
 IPR007192; APC8.
 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF04049; APC8
 PF00515; TPR_1 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS