CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017661
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutathione S-transferase C-terminal domain-containing protein 
Protein Synonyms/Alias
  
Gene Name
 GSTCD 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
133LLELLGFKKTCLKACubiquitination[1]
134LELLGFKKTCLKACAubiquitination[2]
181VEILQLEKKLSEPVRubiquitination[1, 2]
182EILQLEKKLSEPVRVubiquitination[2]
329IQEVPGVKTAASKCGubiquitination[1]
590PQRRLIGKQCMCLVDubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 DOMAIN 130 332 GST C-terminal.  
Keyword
 Alternative splicing; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 633 AA 
Protein Sequence
MKAIKKSLTE EEYLYLDFSH QTEGCIFPLH TSVTLFLLSY CDCKIFKICL VVTKEVSRDS 60
SLLRDDLIQD VEIQIISRQE LPPIVQNCCL PAVVERSDNF CRAGLAVVLR HIIQKSYEAD 120
PLKKELLELL GFKKTCLKAC AEVSQWTRLC ELTIPLAIEN FLRESSDQPP TIPVEILQLE 180
KKLSEPVRVH NDDKLRRQKL KQQKADGVGP PLTKGKAKSK VHTQETSEGL DSSSKSLELK 240
VAFSKLTVQE EPATTNREPS HIRKAKASDL PPLEHVFAEG LYFTLADIVL LPCIHHFLVI 300
ISRKFSEKLV EFPLLASWYQ RIQEVPGVKT AASKCGIQFL HLPKLLTTST EQHPNLCEVP 360
GVEEQSDPLF IGGPRPTMAK LMEKGIEVMF SPHPCPTWTL DWNVLPAAVS PKEGKMSSDR 420
ALRKQQQLNN LVYVVTNQAK PGDRIVDFCS GGGHVGIVLA HMLPSCQVTL IENKELSLIR 480
AKKRSDELGL SNIWFIQANM EYFTGMFNIG VALHACGVAT DMVIEHCIKT RASFVTCPCC 540
YGFIQNTSKF NFPKSEQFKK TLSYKEHMIL CRFADQTAVQ LPPQRRLIGK QCMCLVDLDR 600
ARAAEECGYS VQVISMEPES CSPKNNMIVG VPI 633 
Gene Ontology
  
Interpro
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR025714; Methyltranfer_dom. 
Pfam
 PF13679; Methyltransf_32 
SMART
  
PROSITE
 PS50405; GST_CTER 
PRINTS