CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019415
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative butyrophilin subfamily 2 member A3 
Protein Synonyms/Alias
  
Gene Name
 BTN2A3P 
Gene Synonyms/Alias
 BTN2A3 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
100GRTTFVSKDSRGSVAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 DOMAIN 28 139 Ig-like V-type.
 DOMAIN 281 474 B30.2/SPRY.
 CARBOHYD 45 45 N-linked (GlcNAc...) (Potential).
 CARBOHYD 112 112 N-linked (GlcNAc...) (Potential).
 CARBOHYD 214 214 N-linked (GlcNAc...) (Potential).
 CARBOHYD 220 220 N-linked (GlcNAc...) (Potential).
 DISULFID 50 123 By similarity.  
Keyword
 Complete proteome; Disulfide bond; Glycoprotein; Immunoglobulin domain; Membrane; Polymorphism; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 586 AA 
Protein Sequence
MEPAAALHFS RPASLLLLLS LCALVSAQVT VVGPTDPILA MVGENTTLRC CLSPEENAED 60
MEVRWFQSQF SPAVFVYKGG RERTEEQKEE YRGRTTFVSK DSRGSVALII HNVTAEDNGI 120
YQCYFQEGRS CNEAILHLVV AGLDSEPVIE MRDHEDGGIQ LECISGGWYP KPLTVWRDPY 180
GEVVPALKEV STPDADSLFM VTTAVIIRDK SVRNVSCSIN DTLLGQKKES VIFIPESFMP 240
SRSPCVVILP VIMIILMIPI AICIYWINNL QKEKKDSHLM TFNLCLSLAG WRRTFLHAAN 300
VVLDQDTGHP YLFVSEDKRS VTLDPSRESI PGNPERFDSQ LCVLGQESFA SGKHYLEVDV 360
ENVIEWTVGI CRDNVERKWE VPLLPQNGFW TLEMHKRKYW ALTSLKWILS LEEPLCQVGI 420
FLDYEAGDVS FYNMRDRSHI YTFPHSAFSV PVRPFFSLGS YDSQILICSA FTGASGVTVP 480
EEGWTLHRAG THHSPQNQFP SLTAMETSPG HLSSHCTMPL VEDTPSSPLV TQENIFQLPL 540
SHPLQTSAPV HLLIRCGFSS SFGCNYGMES RHRELVVPQL PARKKV 586 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR001870; B30.2/SPRY.
 IPR003879; Butyrophylin.
 IPR008985; ConA-like_lec_gl_sf.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013106; Ig_V-set.
 IPR003596; Ig_V-set_subgr.
 IPR006574; PRY.
 IPR018355; SPla/RYanodine_receptor_subgr.
 IPR003877; SPRY_rcpt. 
Pfam
 PF00622; SPRY
 PF07686; V-set 
SMART
 SM00406; IGv
 SM00589; PRY
 SM00449; SPRY 
PROSITE
 PS50188; B302_SPRY
 PS50835; IG_LIKE 
PRINTS
 PR01407; BUTYPHLNCDUF.