CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009028
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cyclin-dependent kinases regulatory subunit 2 
Protein Synonyms/Alias
 CKS-2 
Gene Name
 Cks2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
4****MAHKQIYYSDKacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
 Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. 
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 4 4 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Cell cycle; Cell division; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 79 AA 
Protein Sequence
MAHKQIYYSD KYFDEHYEYR HVMLPRELSK QVPKTHLMSE EEWRRLGVQQ SLGWVHYMIH 60
EPEPHILLFR RPLPKEQQK 79 
Gene Ontology
 GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007127; P:meiosis I; IMP:MGI. 
Interpro
 IPR000789; Cyclin-dep_kinase_reg-sub. 
Pfam
 PF01111; CKS 
SMART
 SM01084; CKS 
PROSITE
 PS00944; CKS_1
 PS00945; CKS_2 
PRINTS
 PR00296; CYCLINKINASE.