UniProt Accession

 Q545G0_MOUSE; Q545G0 

Genbank Protein ID

 BC098233; AK010488; AK153162; CH466556 

Genbank Nucleotide ID

 AAH98233.1; BAB26979.1; BAE31772.1; EDL16092.1 

Protein Name

 Proteasome subunit beta type 

Protein Synonyms/Alias

  

Gene Name

 Psmb3 

Gene Synonyms/Alias

 mCG_13231 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
15	GGAVMAMKGKNCVAI	ubiquitination	[1]
17	AVMAMKGKNCVAIAA	ubiquitination	[1]
77	RLNLYELKEGRQIKP	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). 

Sequence Annotation

  

Keyword

 Hydrolase; Nucleus; Protease; Proteasome; Threonine protease. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 205 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005839; C:proteasome core complex; IDA:MGI.
 GO:0004175; F:endopeptidase activity; ISO:MGI.
 GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
 GO:0030163; P:protein catabolic process; TAS:MGI.
 GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro. 

Interpro

 IPR016050; Proteasome_bsu_CS.
 IPR001353; Proteasome_sua/b.
 IPR023333; Proteasome_suB-type. 

Pfam

 PF00227; Proteasome 

SMART

  

PROSITE

 PS00854; PROTEASOME_B_1
 PS51476; PROTEASOME_B_2 

PRINTS