CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012573
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sperm surface protein Sp17 
Protein Synonyms/Alias
 Cancer/testis antigen 22; CT22; Sp17-1; Sperm autoantigenic protein 17; Sperm protein 17 
Gene Name
 SPA17 
Gene Synonyms/Alias
 SP17 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
52SLLEKREKTNFDPAEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity). 
Sequence Annotation
 DOMAIN 114 143 IQ.  
Keyword
 Complete proteome; Membrane; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 151 AA 
Protein Sequence
MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFESLLEKR EKTNFDPAEW 60
GSKVEDRFYN NHAFEEQEPP EKSDPKQEES QISGKEEETS VTILDSSEED KEKEEVAAVK 120
IQAAFRGHIA REEAKKMKTN SLQNEEKEEN K 151 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:BHF-UCL.
 GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
 GO:0031514; C:motile cilium; IDA:BHF-UCL.
 GO:0072372; C:primary cilium; IDA:BHF-UCL.
 GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.
 GO:0007339; P:binding of sperm to zona pellucida; IEA:InterPro.
 GO:0001539; P:ciliary or flagellar motility; IDA:BHF-UCL.
 GO:0007165; P:signal transduction; IEA:InterPro.
 GO:0007338; P:single fertilization; TAS:ProtInc.
 GO:0007283; P:spermatogenesis; TAS:ProtInc. 
Interpro
 IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
 IPR000048; IQ_motif_EF-hand-BS.
 IPR012105; Sp17. 
Pfam
 PF00612; IQ
 PF02197; RIIa 
SMART
 SM00015; IQ
 SM00394; RIIa 
PROSITE
 PS50096; IQ 
PRINTS