CPLM-013900

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-013900

UniProt Accession

SNP47_HUMAN; Q5SQN1; B6EDE0; Q5HYB5; Q5TBZ3; Q8N558; Q8TB31; Q8TCW8; Q8WV46; Q96CQ3; Q96FE1; Q96I66; Q96NU3; Q9BT10; Q9BVB2

Genbank Protein ID

AY090635; BX648570; AL731702; AL136378; AL731702; AL136378; AL136378; AL731702; AL136378; AL136378; AL731702; CH471098; BC001332; BC004418; BC007786; BC011145; BC014059; BC018760; BC025231; BC032775; AK054633; FJ236305

Genbank Nucleotide ID

AAM09082.1; CAI45994.1; CAI21075.1; CAI21075.1; CAI21076.1; CAI21076.1; CAI23069.1; CAI23069.1; CAI23071.1; CAI23072.1; CAI23072.1; EAW69817.1; AAH01332.1; AAH04418.1; AAH07786.2; AAH11145.1; AAH14059.2; AAH18760.2; AAH25231.1; AAH32775.1; BAB70779.1; ACI45237.1

Protein Name

Synaptosomal-associated protein 47

Protein Synonyms/Alias

SNAP-47; Epididymis luminal protein 170; Synaptosomal-associated 47 kDa protein

Gene Name

SNAP47

Gene Synonyms/Alias

C1orf142; HEL170; SVAP1

Created Date

July 27, 2013

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Lysine Modification

Position	Peptide	Type	References
176	GLMAGSQKRLEDTAR	ubiquitination	[1]
345	ILEVQFSKKMELLED	ubiquitination	[1]

Reference

[1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]

Functional Description

Plays a role in intracellular membrane fusion (By similarity).

Sequence Annotation

DOMAIN 154 216 t-SNARE coiled-coil homology 1.
DOMAIN 401 463 t-SNARE coiled-coil homology 2.

Keyword

Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Membrane; Polymorphism; Reference proteome; Repeat.

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

464 AA

Protein Sequence

MRAARRGLHC AGAERPRRRG RLWDSSGVPQ RQKRPGPWRT QTQEQMSRDV CIHTWPCTYY 60
LEPKRRWVTG QLSLTSLSLR FMTDSTGEIL VSFPLSSIVE IKKEASHFIF SSITILEKGH 120
AKHWFSSLRP SRNVVFSIIE HFWRELLLSQ PGAVADASVP RTRGEELTGL MAGSQKRLED 180
TARVLHHQGQ QLDSVMRGLD KMESDLEVAD RLLTELESPA WWPFSSKLWK TPPETKPRED 240
VSMTSCEPFG KEGILIKIPA VISHRTESHV KPGRLTVLVS GLEIHDSSSL LMHRFEREDV 300
DDIKVHSPYE ISIRQRFIGK PDMAYRLISA KMPEVIPILE VQFSKKMELL EDALVLRSAR 360
TSSPAEKSCS VWHAASGLMG RTLHREPPAG DQEGTALHLQ TSLPALSEAD TQELTQGFRP 420
MSLSTQTVLV MLCSESAGAL WRQRLS 446

Gene Ontology

GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.

Interpro

IPR000727; T_SNARE_dom.

Pfam

SMART

PROSITE

PS50192; T_SNARE

PRINTS