CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018955
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein BCL9 homolog 
Protein Synonyms/Alias
 Protein legless 
Gene Name
 lgs 
Gene Synonyms/Alias
 BCL9; CG2041 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
415TKTVGLLKPQFNQHEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Involved in signal transduction through the Wnt pathway. 
Sequence Annotation
 REGION 511 555 ARM-binding.
 MOD_RES 9 9 Phosphoserine.
 MOD_RES 11 11 Phosphothreonine.
 MOD_RES 206 206 Phosphoserine.
 MOD_RES 208 208 Phosphothreonine.
 MOD_RES 210 210 Phosphoserine.
 MOD_RES 883 883 Phosphoserine.
 MOD_RES 905 905 Phosphoserine.
 MOD_RES 911 911 Phosphoserine.  
Keyword
 Complete proteome; Developmental protein; Nucleus; Phosphoprotein; Reference proteome; Segmentation polarity protein; Wnt signaling pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1469 AA 
Protein Sequence
MLSTTMPRSP TQQQPQPNSD ASSTSASGSN PGAAIGNGDS AASRSSPKTL NSEPFSTLSP 60
DQIKLTPEEG TEKSGLSTSD KAATGGAPGS GNNLPEGQTM LRQNSTSTIN SCLVASPQNS 120
SEHSNSSNVS ATVGLTQMVD CDEQSKKNKC SVKDEEAEIS SNKAKGQAAG GGCETGSTSS 180
LTVKEEPTDV LGSLVNMKKE ERENHSPTMS PVGFGSIGNA QDNSATPVKI ERISNDSTTE 240
KKGSSLTMNN DEMSMEGCNQ LNPDFINESL NNPAISSILV SGVGPIPGIG VGAGTGNLLT 300
ANANGISSGS SNCLDYMQQQ NHIFVFSTQL ANKGAESVLS GQFQTIIAYH CTQPATKSFL 360
EDFFMKNPLK INKLQRHNSV GMPWIGMGQV GLTPPNPVAK ITQQQPHTKT VGLLKPQFNQ 420
HENSKRSTVS APSNSFVDQS DPMGNETELM CWEGGSSNTS RSGQNSRNHV DSISTSSESQ 480
AIKILEAAGV DLGQVTKGSD PGLTTENNIV SLQGVKVPDE NLTPQQRQHR EEQLAKIKKM 540
NQFLFPENEN SVGANVSSQI TKIPGDLMMG MSGGGGGSII NPTMRQLHMP GNAKSELLSA 600
TSSGLSEDVM HPGDVISDMG AVIGCNNNQK TSVQCGSGVG VVTGTTAAGV NVNMHCSSSG 660
APNGNMMGSS TDMLASFGNT SCNVIGTAPD MSKEVLNQDS RTHSHQGGVA QMEWSKIQHQ 720
FFEERLKGGK PRQVTGTVVP QQQTPSGSGG NSLNNQVRPL QGPPPPYHSI QRSASVPIAT 780
QSPNPSSPNN LSLPSPRTTA AVMGLPTNSP SMDGTGSLSG SVPQANTSTV QAGTTTVLSA 840
NKNCFQADTP SPSNQNRSRN TGSSSVLTHN LSSNPSTPLS HLSPKEFESF GQSSAGDNMK 900
SRRPSPQGQR SPVNSLIEAN KDVRFAASSP GFNPHPHMQS NSNSALNAYK MGSTNIQMER 960
QASAQGGSVQ FSRRSDNIPL NPNSGNRPPP NKMTQNFDPI SSLAQMSQQL TSCVSSMGSP 1020
AGTGGMTMMG GPGPSDINIE HGIISGLDGS GIDTINQNNC HSMNVVMNSM GPRMLNPKMC 1080
VAGGPNGPPG FNPNSPNGGL RENSIGSGCG SANSSNFQGV VPPGARMMGR MPVNFGSNFN 1140
PNIQVKASTP NTIQYMPVRA QNANNNNNNG ANNVRMPPSL EFLQRYANPQ MGAVGNGSPI 1200
CPPSASDGTP GMPGLMAGPG AGGMLMNSSG EQHQNKITNN PGASNGINFF QNCNQMSIVD 1260
EEGGLPGHDG SMNIGQPSMI RGMRPHAMRP NVMGARMPPV NRQIQFAQSS DGIDCVGDPS 1320
SFFTNASCNS AGPHMFGSAQ QANQPKTQHI KNIPSGMCQN QSGLAVAQGQ IQLHGQGHAQ 1380
GQSLIGPTNN NLMSTAGSVS ATNGVSGINF VGPSSTDLKY AQQYHSFQQQ LYATNTRSQQ 1440
QQHMHQQHQS NMITMPPNLS PNPTFFVNK 1469 
Gene Ontology
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IMP:FlyBase.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IPI:GOC.
 GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IPI:UniProtKB.
 GO:0007367; P:segment polarity determination; IMP:UniProtKB.
 GO:0006351; P:transcription, DNA-dependent; IPI:UniProtKB.
 GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. 
Interpro
 IPR024670; BCL9_beta-catenin-bd_dom. 
Pfam
 PF11502; BCL9 
SMART
  
PROSITE
  
PRINTS