CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023337
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome b5 
Protein Synonyms/Alias
 CYTB5 
Gene Name
 Cyt-b5 
Gene Synonyms/Alias
 CG2140 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
7*MSSEETKTFTRAEVacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 Cytochrome b5 is a membrane-bound hemoprotein which functions as an electron carrier for several membrane-bound oxygenases (By similarity). 
Sequence Annotation
 DOMAIN 6 82 Cytochrome b5 heme-binding.
 METAL 41 41 Iron (heme axial ligand) (By similarity).
 METAL 65 65 Iron (heme axial ligand) (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Electron transport; Endoplasmic reticulum; Heme; Iron; Membrane; Metal-binding; Microsome; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 134 AA 
Protein Sequence
MSSEETKTFT RAEVAKHNTN KDTWLLIHNN IYDVTAFLNE HPGGEEVLIE QAGKDATENF 60
EDVGHSNDAR DMMKKYKIGE LVESERTSVA QKSEPTWSTE QQTEESSVKS WLVPLVLCLV 120
ATLFYKFFFG GAKQ 134 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
 GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.
 GO:0035206; P:regulation of hemocyte proliferation; IMP:FlyBase. 
Interpro
 IPR001199; Cyt_B5-like_heme/steroid-bd.
 IPR018506; Cyt_B5_heme-BS. 
Pfam
 PF00173; Cyt-b5 
SMART
  
PROSITE
 PS00191; CYTOCHROME_B5_1
 PS50255; CYTOCHROME_B5_2 
PRINTS
 PR00363; CYTOCHROMEB5.