CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013937
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sodium/glucose cotransporter 5 
Protein Synonyms/Alias
 Na(+)/glucose cotransporter 5; Solute carrier family 5 member 10 
Gene Name
 Slc5a10 
Gene Synonyms/Alias
 Sglt5 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
44WSACRANKNTVSGYFubiquitination[1]
298ARNLNHAKAGSILASubiquitination[1]
560PNWSLGTKTGDGQTPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 High capacity transporter for mannose and fructose and, to a lesser extent, glucose, AMG, and galactose (By similarity). 
Sequence Annotation
 MOD_RES 141 141 Phosphoserine (By similarity).
 MOD_RES 145 145 Phosphoserine (By similarity).
 MOD_RES 148 148 Phosphothreonine (By similarity).
 CARBOHYD 4 4 N-linked (GlcNAc...) (Potential).
 CARBOHYD 96 96 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell membrane; Complete proteome; Glycoprotein; Ion transport; Membrane; Phosphoprotein; Reference proteome; Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 596 AA 
Protein Sequence
MAGNSTGDAH VPGSQLSVTD IIVISVYFAL NVAVGIWSAC RANKNTVSGY FLAGRDMAWW 60
PIGASLFASS EGSGLFVGLA GSGAAGGLAV AGFEWNATYV LLALAWVFVP IYISSEIVTL 120
PEYIQKRFGG QRIRTYLSVL SLMLSVFTKI SIDLYAGALF VHICLGWNFY LSTILTLAIT 180
ALYTIAGGLA TVIYTDALQT IIMVVGAVIL AVKAFNQIGG YEQLEAAYAQ AIPSRTIPNT 240
TCHLPRADAM HMFRDPSTGD LPWTGMTFGL TIMATWYWCT DQVIVQRSLS ARNLNHAKAG 300
SILASYLKML PMGLMIMPGM ISRVLFPDDV GCVVPSECLR ACGAEIGCSN IAYPKLVMEL 360
MPIGLRGLMI AVMMAALLSS LTSIFNSSST LFTMDIWRQL RPSAGERELL LVGRLVIVVL 420
IGVSVAWIPV LQGSNSGQLF IYMQSVTSSL APPVTAIFIL GIFWRRANEQ GAFWGLMAGL 480
VVGALRLVLE FLYPEPPCGQ IDTRPAPLRS LHYLHFAIAL FLLTCAVMAA GSLLSPPPQQ 540
RQIENLTWWT LAPNWSLGTK TGDGQTPQKR AFWARVCNVN AIFLMCVNIF FYAYFA 596 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
 GO:0055085; P:transmembrane transport; IEA:InterPro. 
Interpro
 IPR001734; Na/solute_symporter.
 IPR018212; Na/solute_symporter_CS.
 IPR019900; Na/solute_symporter_subgr. 
Pfam
 PF00474; SSF 
SMART
  
PROSITE
 PS00457; NA_SOLUT_SYMP_2
 PS50283; NA_SOLUT_SYMP_3 
PRINTS