UniProt Accession

 OSGI1_HUMAN; Q9UJX0; Q52M33; Q86UQ1; Q96S88; Q9BZ70 

Genbank Protein ID

 AF334780; AY258066; AY258067; AY258068; AY037158; AK290383; AC040169; CH471114; BC093687; BC113417; BC032476; AF191740 

Genbank Nucleotide ID

 AAK01722.2; AAP14662.1; AAP14663.1; AAP14664.1; AAK67637.1; BAF83072.1; EAW95511.1; AAH93687.2; AAI13418.2; AAH32476.1; AAF06662.1 

Protein Name

 Oxidative stress-induced growth inhibitor 1 

Protein Synonyms/Alias

 Ovary, kidney and liver protein 38; huOKL38; Pregnancy-induced growth inhibitor OKL38 

Gene Name

 OSGIN1 

Gene Synonyms/Alias

 OKL38 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
193	MKSVLTWKHRKEHAI	ubiquitination	[1]
243	EVKDWMQKKRRGLRN	ubiquitination	[2]
268	YYRDYVVKKGLGHNF	ubiquitination	[2]
414	LVFNQLPKMLYPEYH	ubiquitination	[1, 2, 3]
422	MLYPEYHKVHQMMRE	ubiquitination	[2]
453	RHQLLCFKEDCQAVF	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 Regulates the differentiation and proliferation of normal cells through the regulation of cell death. 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Developmental protein; Differentiation; Growth regulation; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 560 AA 

Protein Sequence

Gene Ontology

 GO:0008083; F:growth factor activity; IDA:UniProtKB.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS