CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030615
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ42590 fis, clone BRACE3009708, highly similar to Sodium/potassium-transporting ATPase alpha-2chain (EC 3.6.3.9) 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
623VDDSPALKKADIGIAubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Hydrolase; Membrane; Nucleotide-binding; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 920 AA 
Protein Sequence
MGRGAGREYS PAATTAENGG GKKKQKEKEL DELKKEVVIV TGCFSYYQEA KSSKIMDSFK 60
NMVPQQALVI REGEKMQINA EEVVVGDLVE VKGGDRVPAD LRIISSHGCK VDNSSLTGEP 120
EPQTRSPEFT HENPLETRNI CFFSTNCVEG TARGIVIATG DRTVMGRIAT LASGLEVGRT 180
PIAMEIEHFI QLITGVAVFL GVSFFVLSLI LGYSWLEAVI FLIGIIVANV PEGLLATVTV 240
CLTLTAKRMA RKNCLVKNLE AVETLGSTST ICSDKTGTLT QNRMTVAHMW FDNQIHEADT 300
TEDQSGATFD KRSPTWTALS RIAGLCNRAV FKAGQENISV SKRDTAGDAS ESALLECIEL 360
SCGSVRKMRD RNPKVAEIPF NSTNKYQLSI HEREDSPQSH VLVMKGAPER ILDRCSTILV 420
QGKEIPLDKE MQDAFQNAYM ELGGLGERVL GFCQLNLPSG KFPRGFKFDT DELNFPTEKL 480
CFVGLMSMID PPRAAVPDAV GKCRSAGIKV IMVTGDHPIT AKAIAKGVGI ISEGNETVED 540
IAARLNIPMS QVNPREAKAC VVHGSDLKDM TSEQLDEILK NHTEIVFART SPQQKLIIVE 600
GCQRQGAIVA VTGDGVDDSP ALKKADIGIA MGISGSDVSK QAADMILLDD NFASIVTGVE 660
EGRLIFDNLK KSIAYTLTSN IPEITPFLLF IIANIPLPLG TVTILCIDLG TDMVPAISLA 720
YEAAESDIMK RQPRNSQTDK LVNERLISMA YGQIGMIQAL GGFFTYFVIL AENGFLPSRL 780
LGIRLDWDDR TMNDLEDSYG QEWTYEQRKV VEFTCHTAFF ASIVVVQWAD LIICKTRRNS 840
VFQQGMKNKI LIFGLLEETA LAAFLSYCPG MGVALRMYPL KVTWWFCAFP YSLLIFIYDE 900
VRKLILRRYP GGWVEKETYY 920 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0015077; F:monovalent inorganic cation transmembrane transporter activity; IEA:InterPro.
 GO:0006754; P:ATP biosynthetic process; IEA:InterPro. 
Interpro
 IPR006068; ATPase_P-typ_cation-transptr_C.
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR005775; ATPase_P-typ_Na/K_IIC.
 IPR018303; ATPase_P-typ_P_site.
 IPR023298; ATPase_P-typ_TM_dom.
 IPR008250; ATPase_P-typ_transduc_dom_A.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00689; Cation_ATPase_C
 PF00122; E1-E2_ATPase
 PF00702; Hydrolase 
SMART
  
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS
 PR00119; CATATPASE.