CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038636
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cysteine-rich protein 2-binding protein 
Protein Synonyms/Alias
  
Gene Name
 Csrp2bp 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
19TLKVKASKPTLDPIIacetylation[1]
64KDIRRAQKEAAGLLDacetylation[1, 2]
80STSSTPVKFISRGRRacetylation[1, 3]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 568 AA 
Protein Sequence
MRPEGEKLAA STLKVKASKP TLDPIITVEG LRKRASRNPV ESAMELKEKR SRTQEAKDIR 60
RAQKEAAGLL DRSTSSTPVK FISRGRRPDL ILEKGEVIDF SSLSSSDRTP LTSPSPSPSL 120
DFSAPGTPAS HSATPSLLSE ADLIPDVMPP QALFHDDDEL EGDGVIDPGM EYIPPPAGSA 180
SGLLGSRKKV RAPEQIKQEV DSEEEKPDRM DGDSEDTDSN ISLHTRAREK RKPPLEKDMK 240
PKGPRYTPVS IYEEKLLLKR LEACPGAVAM TPEARRLKRK LIVRQAKRDR GLPLFDLDEV 300
VNAALLLVDG IYGAKDGGAS RLAAGQATYR TTCQDFRILD RYQTALPARK GFRHQTTRFL 360
YRLVGSEDLA VDQSIISPYT SRILKPYIRR DYETKPPKLQ LLSQIRSHLH RSDPHWTPGP 420
DAPLDYCYVR PNHIPTINSM CQEFFWPGID LSECLQYPDF SVVVLYKKVI VAFGFMVPDV 480
KYNEAYISFL LVHPEWRRAG IATFMIYHLI QTCMGKDVTL HVSASNPAML LYQKFGFKTE 540
EYVLDFYDKY YPLESTECKH AFFLRLRR 568 
Gene Ontology
 GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:MGI.
 GO:0004402; F:histone acetyltransferase activity; ISO:MGI.
 GO:0009790; P:embryo development; IMP:MGI.
 GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:MGI.
 GO:0043966; P:histone H3 acetylation; IEA:Compara. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR000182; GNAT_dom. 
Pfam
 PF00583; Acetyltransf_1 
SMART
  
PROSITE
 PS51186; GNAT 
PRINTS