CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024589
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Stathmin 
Protein Synonyms/Alias
  
Gene Name
 STMN1 
Gene Synonyms/Alias
 STMN 
Created Date
 July 27, 2013 
Organism
 Gecko japonicus (Japanese gecko) 
NCBI Taxa ID
 146911 
Lysine Modification
Position
Peptide
Type
References
9ASSDIQVKELEKRASubiquitination[1]
29LILSPRSKESVPEFPubiquitination[1]
52LSLEEIQKKLEAAEEubiquitination[1]
85HEKEVLQKAIEENNNubiquitination[1]
95EENNNFSKMAEEKLTubiquitination[1]
119REAQMAAKLERLREKubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
 Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules (By similarity). 
Sequence Annotation
 DOMAIN 4 145 SLD.
 MOD_RES 16 16 Phosphoserine (By similarity).
 MOD_RES 25 25 Phosphoserine (By similarity).
 MOD_RES 28 28 Phosphoserine (By similarity).
 MOD_RES 38 38 Phosphoserine (By similarity).
 MOD_RES 46 46 Phosphoserine (By similarity).
 MOD_RES 63 63 Phosphoserine (By similarity).
 MOD_RES 146 146 Phosphothreonine (By similarity).  
Keyword
 Coiled coil; Cytoplasm; Cytoskeleton; Microtubule; Phosphoprotein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 149 AA 
Protein Sequence
MASSDIQVKE LEKRASGQAF ELILSPRSKE SVPEFPLSPP KKKDLSLEEI QKKLEAAEER 60
RKSHEAEVLK QLAEKREHEK EVLQKAIEEN NNFSKMAEEK LTHKMEANKE NREAQMAAKL 120
ERLREKDKHI EEVRKNKESK DPADETEAD 149 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:InterPro. 
Interpro
 IPR000956; Stathmin_fam. 
Pfam
 PF00836; Stathmin 
SMART
  
PROSITE
 PS00563; STATHMIN_1
 PS01041; STATHMIN_2
 PS51663; STATHMIN_3 
PRINTS
 PR00345; STATHMIN.