Tag | Content |
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CPLM ID | CPLM-024589 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Stathmin |
Protein Synonyms/Alias | |
Gene Name | STMN1 |
Gene Synonyms/Alias | STMN |
Created Date | July 27, 2013 |
Organism | Gecko japonicus (Japanese gecko) |
NCBI Taxa ID | 146911 |
Lysine Modification | Position | Peptide | Type | References |
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9 | ASSDIQVKELEKRAS | ubiquitination | [1] | 29 | LILSPRSKESVPEFP | ubiquitination | [1] | 52 | LSLEEIQKKLEAAEE | ubiquitination | [1] | 85 | HEKEVLQKAIEENNN | ubiquitination | [1] | 95 | EENNNFSKMAEEKLT | ubiquitination | [1] | 119 | REAQMAAKLERLREK | ubiquitination | [1] |
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Reference | [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA. Mol Cell Proteomics. 2012 May;11(5):148-59. [ PMID: 22505724] |
Functional Description | Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules (By similarity). |
Sequence Annotation | DOMAIN 4 145 SLD. MOD_RES 16 16 Phosphoserine (By similarity). MOD_RES 25 25 Phosphoserine (By similarity). MOD_RES 28 28 Phosphoserine (By similarity). MOD_RES 38 38 Phosphoserine (By similarity). MOD_RES 46 46 Phosphoserine (By similarity). MOD_RES 63 63 Phosphoserine (By similarity). MOD_RES 146 146 Phosphothreonine (By similarity). |
Keyword | Coiled coil; Cytoplasm; Cytoskeleton; Microtubule; Phosphoprotein. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 149 AA |
Protein Sequence | MASSDIQVKE LEKRASGQAF ELILSPRSKE SVPEFPLSPP KKKDLSLEEI QKKLEAAEER 60 RKSHEAEVLK QLAEKREHEK EVLQKAIEEN NNFSKMAEEK LTHKMEANKE NREAQMAAKL 120 ERLREKDKHI EEVRKNKESK DPADETEAD 149 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |