CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006720
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HTH-type transcriptional regulator DctR 
Protein Synonyms/Alias
  
Gene Name
 dctR 
Gene Synonyms/Alias
 yhiF; b3507; JW3475 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
139TTEDILEKLKISLKTacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 May act as a transcriptional regulator of dctA. 
Sequence Annotation
 DOMAIN 109 174 HTH luxR-type.
 DNA_BIND 133 152 H-T-H motif (By similarity).  
Keyword
 Complete proteome; DNA-binding; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 176 AA 
Protein Sequence
MFLIITRDTM FFTAMKNILS KGNVVHIQNE EEIDVMLHQN AFVIIDTLMN NVFHSNFLTQ 60
IERLKPVHVI IFSPFNIKRC LGKVPVTFVP RTITIIDFVA LINGSYCSVP EAAVSLSRKQ 120
HQVLSCIANQ MTTEDILEKL KISLKTFYCH KHNIMMILNL KRINELVRHQ HIDYLV 176 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0043471; P:regulation of cellular carbohydrate catabolic process; IGI:EcoCyc.
 GO:0001101; P:response to acid; IMP:EcoCyc.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR016032; Sig_transdc_resp-reg_C-effctor.
 IPR000792; Tscrpt_reg_LuxR_C.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00196; GerE 
SMART
 SM00421; HTH_LUXR 
PROSITE
 PS00622; HTH_LUXR_1
 PS50043; HTH_LUXR_2 
PRINTS