UniProt Accession

 ARH38_HUMAN; Q9NXL2; C9JIB4 

Genbank Protein ID

 AK000191; AC004066; AC105391; CH471057; BC105695 

Genbank Nucleotide ID

 BAA90998.1; EAX06187.1; AAI05696.1 

Protein Name

 Rho guanine nucleotide exchange factor 38 

Protein Synonyms/Alias

  

Gene Name

 ARHGEF38 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
219	SHCIQSLK*******	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 May act as a guanine-nucleotide releasing factor (By similarity). 

Sequence Annotation

 DOMAIN 94 219 DH.  

Keyword

 Alternative splicing; Complete proteome; Guanine-nucleotide releasing factor; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 219 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. 

Interpro

 IPR000219; DH-domain. 

Pfam

 PF00621; RhoGEF 

SMART

  

PROSITE

 PS00741; DH_1
 PS50010; DH_2 

PRINTS