| Tag | Content |
|---|
| CPLM ID | CPLM-005996 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Crotonobetainyl-CoA:carnitine CoA-transferase |
Protein Synonyms/Alias | |
Gene Name | caiB |
Gene Synonyms/Alias | yaaN; b0038; JW0037 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 75 | ALSLNIFKDEGREAF | acetylation | [1] | | 309 | THTIAEVKERFAELN | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl- CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl- CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. |
Sequence Annotation | ACT_SITE 169 169 Nucleophile.
BINDING 97 97 Coenzyme A.
BINDING 104 104 Coenzyme A. |
Keyword | 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 405 AA |
Protein Sequence | MDHLPMPKFG PLAGLRVVFS GIEIAGPFAG QMFAEWGAEV IWIENVAWAD TIRVQPNYPQ 60
LSRRNLHALS LNIFKDEGRE AFLKLMETTD IFIEASKGPA FARRGITDEV LWQHNPKLVI 120
AHLSGFGQYG TEEYTNLPAY NTIAQAFSGY LIQNGDVDQP MPAFPYTADY FSGLTATTAA 180
LAALHKVRET GKGESIDIAM YEVMLRMGQY FMMDYFNGGE MCPRMSKGKD PYYAGCGLYK 240
CADGYIVMEL VGITQIEECF KDIGLAHLLG TPEIPEGTQL IHRIECPYGP LVEEKLDAWL 300
ATHTIAEVKE RFAELNIACA KVLTVPELES NPQYVARESI TQWQTMDGRT CKGPNIMPKF 360
KNNPGQIWRG MPSHGMDTAA ILKNIGYSEN DIQELVSKGL AKVED 405 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0008735; F:carnitine dehydratase activity; EXP:EcoliWiki. GO:0008410; F:CoA-transferase activity; IEA:HAMAP. GO:0042413; P:carnitine catabolic process; EXP:EcoliWiki. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |