CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006421
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial import receptor subunit TOM20 
Protein Synonyms/Alias
 Mitochondrial 20 kDa outer membrane protein; Protein MAS20; Translocase of outer membrane 20 kDa subunit 
Gene Name
 TOM20 
Gene Synonyms/Alias
 MAS20; MOM19; YGR082W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
109RLSMQQGKELEAASKubiquitination[1]
169VKGVVGSKAESDAVAubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Central component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. 
Sequence Annotation
 MOD_RES 172 172 Phosphoserine.  
Keyword
 Complete proteome; Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 183 AA 
Protein Sequence
MSQSNPILRG LAITTAIAAL SATGYAIYFD YQRRNSPQFR KVLRQRAKEQ AKMEEQAKTH 60
AKEVKLQKVT EFLSMELAKD PIPSDPSERE ATFTTNVENG ERLSMQQGKE LEAASKFYKA 120
LTVYPQPADL LGIYQRSIPE AIYEYIILMI AILPPANVAS FVKGVVGSKA ESDAVAEAND 180
IDD 183 
Gene Ontology
 GO:0031307; C:integral to mitochondrial outer membrane; IDA:SGD.
 GO:0005742; C:mitochondrial outer membrane translocase complex; IDA:SGD.
 GO:0030943; F:mitochondrion targeting sequence binding; IDA:SGD.
 GO:0070096; P:mitochondrial outer membrane translocase complex assembly; IMP:SGD.
 GO:0030150; P:protein import into mitochondrial matrix; IMP:SGD.
 GO:0016031; P:tRNA import into mitochondrion; IMP:SGD. 
Interpro
 IPR002056; MAS20_rcpt-related.
 IPR023392; Tom20_dom. 
Pfam
 PF02064; MAS20 
SMART
  
PROSITE
  
PRINTS
 PR00351; OM20RECEPTOR.