| Tag | Content |
|---|
| CPLM ID | CPLM-005250 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Acetylornithine deacetylase |
Protein Synonyms/Alias | AO; Acetylornithinase; N-acetylornithinase; NAO |
Gene Name | argE |
Gene Synonyms/Alias | b3957; JW3929 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 4 | ****MKNKLPPFIEI | acetylation | [1] | | 104 | TLTEHDGKLYGLGTA | acetylation | [1] | | 131 | LRDVDVTKLKKPLYI | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde. |
Sequence Annotation | ACT_SITE 82 82 By similarity.
ACT_SITE 144 144 Proton acceptor (By similarity).
METAL 80 80 Cobalt or zinc 1 (By similarity).
METAL 112 112 Cobalt or zinc 1 (By similarity).
METAL 112 112 Cobalt or zinc 2 (By similarity).
METAL 145 145 Cobalt or zinc 2 (By similarity).
METAL 169 169 Cobalt or zinc 1 (By similarity).
METAL 355 355 Cobalt or zinc 2 (By similarity). |
Keyword | Amino-acid biosynthesis; Arginine biosynthesis; Cobalt; Complete proteome; Cytoplasm; Hydrolase; Metal-binding; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 383 AA |
Protein Sequence | MKNKLPPFIE IYRALIATPS ISATEEALDQ SNADLITLLA DWFKDLGFNV EVQPVPGTRN 60
KFNMLASIGQ GAGGLLLAGH TDTVPFDDGR WTRDPFTLTE HDGKLYGLGT ADMKGFFAFI 120
LDALRDVDVT KLKKPLYILA TADEETSMAG ARYFAETTAL RPDCAIIGEP TSLQPVRAHK 180
GHISNAIRIQ GQSGHSSDPA RGVNAIELMH DAIGHILQLR DNLKERYHYE AFTVPYPTLN 240
LGHIHGGDAS NRICACCELH MDIRPLPGMT LNELNGLLND ALAPVSERWP GRLTVDELHP 300
PIPGYECPPN HQLVEVVEKL LGAKTEVVNY CTEAPFIQTL CPTLVLGPGS INQAHQPDEY 360
LETRFIKPTR ELITQVIHHF CWH 383 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0008777; F:acetylornithine deacetylase activity; IDA:EcoliWiki. GO:0050897; F:cobalt ion binding; IDA:EcoCyc. GO:0008237; F:metallopeptidase activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IDA:EcoCyc. GO:0006526; P:arginine biosynthetic process; IDA:EcoCyc. GO:0006508; P:proteolysis; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |