CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026274
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCM10 minichromosome maintenance deficient 10 (S. cerevisiae), isoform CRA_b 
Protein Synonyms/Alias
 Protein MCM10 homolog 
Gene Name
 MCM10 
Gene Synonyms/Alias
 hCG_40780 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
312PQSVNSGKTFSIWKLubiquitination[1, 2]
359ILNANPMKPKDGSEEubiquitination[1]
394GTCKAKKKNGEPCTQubiquitination[1]
480AAAVAPKKKIQTTLSubiquitination[1]
519LSCSEEFKELMDLPTubiquitination[1, 2]
565SALLKQQKQRMLEMRubiquitination[1]
626APATMTPKLGRGVLEubiquitination[1, 2, 3]
657LSALAEAKKLAAITKubiquitination[1]
658SALAEAKKLAAITKLubiquitination[1, 2]
664KKLAAITKLRAKGQVubiquitination[1]
694PQDILEVKERVEKNTubiquitination[1]
732LESEEFQKILKAKSKubiquitination[1]
762YFEPLVKKEQMEEKMubiquitination[1]
810YHWHDGVKRFFKCPCubiquitination[1]
814DGVKRFFKCPCGNRSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 855 AA 
Protein Sequence
MDEEEDNLSL LTALLEENES ALDCNSEENN FLTRENGEPD AFDELFDADG DGESYTEEAD 60
DGETGETRDE KENLATLFGD MEDLTDEEEV PASQSTENRV LPAPAPRREK TNEELQEELR 120
NLQEQMKALQ EQLKVTTIKQ TASPARLQKS PEKSPRPPLK ERRVQRIQES TCFSAELDVP 180
ALPRTKRVAR TPKASPPDPK SSSSRMTSAP SQPLQTISRN KPSGITRGQI VGTPGSSGET 240
TQPICVEAFS GLRLRRPRVS STEMNKKMTG RKLIRLSQIK EKMAREKLEE IDWVTFGVIL 300
KKVTPQSVNS GKTFSIWKLN DLRDLTQCVS LFLFGEVHKA LWKTEQGTVV GILNANPMKP 360
KDGSEEVCLS IDHPQKVLIM GEALDLGTCK AKKKNGEPCT QTVNLRDCEY CQYHVQAQYK 420
KLSAKRADLQ STFSGGRIPK KFARRGTSLK ERLCQDGFYY GGVSSASYAA SIAAAVAPKK 480
KIQTTLSNLV VKGTNLIIQE TRQKLGIPQK SLSCSEEFKE LMDLPTCGAR NLKQHLAKAT 540
ASGIMGSPKP AIKSISASAL LKQQKQRMLE MRRRKSEEIQ KRFLQSSSEV ESPAVPSSSR 600
QPPAQPPRTG SEFPRLEGAP ATMTPKLGRG VLEGDDVLFY DESPPPRPKL SALAEAKKLA 660
AITKLRAKGQ VLTKTNPNSI KKKQKDPQDI LEVKERVEKN TMFSSQAEDE LEPARKKRRE 720
QLAYLESEEF QKILKAKSKH TGILKEAEAE MQERYFEPLV KKEQMEEKMR NIREVKCRVV 780
TCKTCAYTHF KLLETCVSEQ HEYHWHDGVK RFFKCPCGNR SISLDRLPNK HCSNCGLYKW 840
ERDGMLKVCH LRTNF 855 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0006260; P:DNA replication; IEA:InterPro. 
Interpro
 IPR015411; Rep_factor_Mcm10.
 IPR015408; Znf_Mcm10/DnaG. 
Pfam
 PF09332; Mcm10
 PF09329; zf-primase 
SMART
  
PROSITE
  
PRINTS