| Tag | Content |
|---|
| CPLM ID | CPLM-042037 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | G protein-coupled receptor kinase 5 |
Protein Synonyms/Alias | |
Gene Name | GRK5 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 338 | EEGAAEVKRHPFFRN | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | |
Keyword | ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 485 AA |
Protein Sequence | MTKYLTPKSP VFIAQVGQDL VSQTEEKLLQ KPCKELFSAC AQSVHEYLRG EPFHEYLDSM 60
FFDRFLQWKW LERQPVTKNT FRQYRVLGKG GFGEVCACQV RATGKMYACK RLEKKRIKKR 120
KGESMALNEK QILEKVNSQF VVNLAYAYET KDALCLVLTI MNGGDLKFHI YNMGNPGFEE 180
ERALFYAAEI LCGLEDLHRE NTVYRDLKPE NILLDDYGHI RISDLGLAVK IPEGDLIRGR 240
VGTVGYMAPE VLNNQRYGLS PDYWGLGCLI YEMIEGQSPF RGRKEKVKRE EVDRRVLETE 300
EVYSHKFSEE AKSICKMLLT KDAKQRLGCQ EEGAAEVKRH PFFRNMNFKR LEAGMLDPPF 360
VPDPRAVYCK DVLDIEQFST VKGVNLDHTD DDFYSKFSTG SVSIPWQNEM IETECFKELN 420
VFGPNGTLPP DLNRNHPPEP PKKGLLQRLF KRQHQNNSKS SPSSKTSFNH HINSNHVSSN 480
STGSS 485 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004703; F:G-protein coupled receptor kinase activity; IEA:InterPro. GO:0007165; P:signal transduction; IEA:InterPro. GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |