CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038655
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Fragile X mental retardation protein 1 homolog 
Protein Synonyms/Alias
  
Gene Name
 Fmr1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
17GSNGAFYKAFVKDVHubiquitination[1]
130KDTFHKIKLEVPEDLubiquitination[1]
310LIQEIVDKSGVVRVRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 631 AA 
Protein Sequence
MEELVVEVRG SNGAFYKAFV KDVHEDSITV AFENNWQPER QIPFHDVRFP PPVGYNKDIN 60
ESDEVEVYSR ANEKEPCCWW LAKVRMIKGE FYVIEYAACD ATYNEIVTIE RLRSVNPNKP 120
ATKDTFHKIK LEVPEDLRQM CAKESAHKDF KKAVGAFSVT YDPENYQLVI LSINEVTSKR 180
AHMLIDMHFR SLRTKLSLIL RNEEASKQLE SSRQLASRFH EQFIVREDLM GLAIGTHGAN 240
IQQARKVPGV TAIDLDEDTC TFHIYGEDQD AVKKARSFLE FAEDVIQVPR NLVGKVIGKN 300
GKLIQEIVDK SGVVRVRIEA ENEKSVPQEE EIMPPSSLPS NNSRVGPNSS EEKKHLDTKE 360
NTHFSQPNST KVQRVLVVSS IVAGGPQKPE PKAWQGMVPF VFVGTKDSIA NATVLLDYHL 420
NYLKEVDQLR LERLQIDEQL RQIGASSRPP PNRTDKEKGY VTDDGQGMGR GSRPYRNRGH 480
GRRGPGYTSG TNSEASNASE TESDHRDELS DWSLAPTEEE RESFLRRGDG RRRGGGGRGQ 540
GGRGRGGGFK GNDDHSRTDN RPRNPREAKG RTADGSLQIT VNCNNEKTVH TKPLQSASSE 600
GSRLRTGKDR NQKKEKPDSV DGLQPLVNGV P 631 
Gene Ontology
 GO:0010494; C:cytoplasmic stress granule; IDA:MGI.
 GO:0071598; C:neuronal ribonucleoprotein granule; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0007417; P:central nervous system development; IMP:MGI. 
Interpro
 IPR008395; Agenet-like_dom.
 IPR022034; Frag_X_MRP_fam.
 IPR004087; KH_dom.
 IPR004088; KH_dom_type_1. 
Pfam
 PF05641; Agenet
 PF12235; FXR1P_C
 PF00013; KH_1 
SMART
 SM00322; KH 
PROSITE
 PS51641; AGENET_LIKE
 PS50084; KH_TYPE_1 
PRINTS