CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036692
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Pantothenate kinase 3 
Protein Synonyms/Alias
  
Gene Name
 PANK3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
31QEEVESLKSIRKYLTubiquitination[1, 2]
35ESLKSIRKYLTSNVAubiquitination[3, 4]
56RDVHLELKDLTLFGRubiquitination[3]
105ATGGGAYKFEKDFRTubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 122 AA 
Protein Sequence
MDIGGTLVKL SYFEPIDITA EEEQEEVESL KSIRKYLTSN VAYGSTGIRD VHLELKDLTL 60
FGRRGNLHFI RFPTQDLPTF IQMGRDKNFS TLQTVLCATG GGAYKFEKDF RTIGNLHLHK 120
LD 122 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004594; F:pantothenate kinase activity; IEA:InterPro.
 GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro. 
Interpro
 IPR004567; Type_II_PanK. 
Pfam
 PF03630; Fumble 
SMART
  
PROSITE
  
PRINTS