CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003475
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Exodeoxyribonuclease 10 
Protein Synonyms/Alias
 Exodeoxyribonuclease X; Exo X; Exonuclease X 
Gene Name
 exoX 
Gene Synonyms/Alias
 yobC; b1844; JW1833 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
111RRLWPGIKYSNMALYacetylation[1]
119YSNMALYKTRKLNVQacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Capable of degrading both single-strand and double- strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. 
Sequence Annotation
  
Keyword
 Complete proteome; DNA damage; DNA repair; Exonuclease; Hydrolase; Magnesium; Nuclease; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 220 AA 
Protein Sequence
MLRIIDTETC GLQGGIVEIA SVDVIDGKIV NPMSHLVRPD RPISPQAMAI HRITEAMVAD 60
KPWIEDVIPH YYGSEWYVAH NASFDRRVLP EMPGEWICTM KLARRLWPGI KYSNMALYKT 120
RKLNVQTPPG LHHHRALYDC YITAALLIDI MNTSGWTAEQ MADITGRPSL MTTFTFGKYR 180
GKAVSDVAER DPGYLRWLFN NLDSMSPELR LTLKHYLENT 220 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008408; F:3'-5' exonuclease activity; IDA:EcoCyc.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006298; P:mismatch repair; IDA:EcoCyc. 
Interpro
 IPR006055; Exonuclease.
 IPR013520; Exonuclease_RNaseT/DNA_pol3.
 IPR012337; RNaseH-like_dom. 
Pfam
 PF00929; RNase_T 
SMART
 SM00479; EXOIII 
PROSITE
  
PRINTS