CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015276
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable tRNA threonylcarbamoyladenosine biosynthesis protein Osgepl1 
Protein Synonyms/Alias
 t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgepl1 
Gene Name
 Osgepl1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
299ATACHLAKRTHRAILacetylation[1]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753
Functional Description
 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity). 
Sequence Annotation
 MOD_RES 7 7 Phosphothreonine.  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome; tRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 414 AA 
Protein Sequence
MLMLRRTAGA IPKPPKSKVY GFLRRFSVHP RTLSCHKLVL GIETSCDDTG AAVVDETGNV 60
LGEALHSQTQ VHLKTGGIVP PVAQQLHREN IQRIVEETLS ACRITPSDLS AIATTIKPGL 120
ALSLGVGLSF SLQLVNQFKK PFIPIHHMEA HALTIRLTNK VEFPFLVLLI SGGHCLLALV 180
QGVSDFLLLG KSLDIAPGDM LDKVARRLSL IKHPECSTMS GGKAIEQLAK DGNRFHFTIN 240
PPMQNAKNCD FSFTGLQHIT DKLITHKEKE EGIEKGQILS SAADIAAAVQ HATACHLAKR 300
THRAILFCKQ KNLLSPANAV LVVSGGVASN LYIRKALEIV ANATQCTLLC PPPRLCTDNG 360
IMIAWNGIER LRAGLGVLHD VEDIRYEPKC PLGVDISREV AEAAIKVPRL KMAL 414 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. 
Interpro
 IPR000905; Gcp-like_dom.
 IPR017861; KAE1/YgjD. 
Pfam
 PF00814; Peptidase_M22 
SMART
  
PROSITE
  
PRINTS
 PR00789; OSIALOPTASE.