CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010995
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein MUK1 
Protein Synonyms/Alias
  
Gene Name
 MUK1 
Gene Synonyms/Alias
 YPL070W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
427KLTVNESKILENSISubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Putative GTPase-activating protein. 
Sequence Annotation
 DOMAIN 273 414 VPS9.
 MOD_RES 67 67 Phosphoserine.
 MOD_RES 163 163 Phosphoserine.
 MOD_RES 185 185 Phosphoserine.
 MOD_RES 245 245 Phosphoserine.  
Keyword
 Complete proteome; Cytoplasm; GTPase activation; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 612 AA 
Protein Sequence
MARQLFTPPI TNPRFDPNQS IRESYKNTTG GMQFQQNLHE DQNDNERSSC DGDENSTTGE 60
RLENNKSPIL TKQEIDEALN TVTNLPPELS KLIDIFIDDL KQPKYVRPLS VLQLSSLFQS 120
FYIKFDKASF QHVSSANNNG YYFSGGGSSS FLAAKETLSS GLSGIFGRSR SSSGNSLMRP 180
RRSSSLFSNE SISNSTNATQ MLSPEEIKKQ LKINELNNMK IEKYMELCER DVFKKILIVG 240
TSVSSPNKMK TFKPHQLQTF KVGNLFRNSV EFTEYNKLLN EKILCLSKLS TMNKINLIKF 300
LSLNNGIDPE PKFEEIKDIL YEFTYHSISP CEKIKALLKL HEIMTYSQEM SNDDYLSLLI 360
YYIITIVPRD IFLNAEFIRL FRYKKKLVET ESFALTNLEA ALVFVEGLTK NDFSNELQDK 420
LTVNESKILE NSISSRVSLP SKTAIMHKNN GNNGSNLGDI VTPTIQRPDV TRSNSYDGFR 480
TVFDSSLKNI IGKIRSYTPP HPNNTSNNNL HSSNNLNIPR SSSQLSMELS NRDTTEMSRD 540
GSRSTSSSSR SSASLEHGNR EFTGDLTVTA SINGADKKEF QKSWKKYKGY KFEDLTICEL 600
RDLFEIYQKM MQ 612 
Gene Ontology
 GO:0005829; C:cytosol; IDA:SGD.
 GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
 GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:SGD.
 GO:0006895; P:Golgi to endosome transport; IGI:SGD.
 GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IGI:SGD.
 GO:0043547; P:positive regulation of GTPase activity; IEA:GOC.
 GO:0036010; P:protein localization to endosome; IGI:SGD. 
Interpro
 IPR003123; VPS9.
 IPR013995; VPS9_subgr. 
Pfam
 PF02204; VPS9 
SMART
 SM00167; VPS9 
PROSITE
 PS51205; VPS9 
PRINTS