UniProt Accession

 CH10_MYCTU; P09621; L0TFJ8 

Genbank Protein ID

 X60350; M25258; X13739; AE000516; AL123456 

Genbank Nucleotide ID

 CAA42908.1; AAA25340.1; CAA32003.1; AAK47865.1; CCP46240.1 

Protein Name

 10 kDa chaperonin 

Protein Synonyms/Alias

 10 kDa antigen; BCG-A heat shock protein; GroES protein; Protein Cpn10 

Gene Name

 groS 

Gene Synonyms/Alias

 cpn10; groES; mopB; Rv3418c; MT3527; MTCY78.11 

Created Date

 July 27, 2013 

Organism

 Mycobacterium tuberculosis 

NCBI Taxa ID

 1773 

Lysine Modification

Position	Peptide	Type	References
100	DVLAVVSK*******	pupylation	[1]

Reference

 [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036] 

Functional Description

 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. 

Sequence Annotation

 CROSSLNK 100 100 Isoglutamyl lysine isopeptide (Lys-Gln)  

Keyword

 3D-structure; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Isopeptide bond; Reference proteome; Stress response; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 100 AA 

Protein Sequence

Gene Ontology

 GO:0005618; C:cell wall; IDA:MTBBASE.
 GO:0005829; C:cytosol; IDA:MTBBASE.
 GO:0005576; C:extracellular region; IDA:MTBBASE.
 GO:0005886; C:plasma membrane; IDA:MTBBASE.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IDA:MTBBASE.
 GO:0034605; P:cellular response to heat; IMP:MTBBASE.
 GO:0040007; P:growth; IMP:MTBBASE.
 GO:0006457; P:protein folding; IEA:HAMAP.
 GO:0051260; P:protein homooligomerization; IPI:MTBBASE.
 GO:0006355; P:regulation of transcription, DNA-dependent; IMP:MTBBASE.
 GO:0046677; P:response to antibiotic; IEP:MTBBASE. 

Interpro

 IPR020818; Chaperonin_Cpn10.
 IPR018369; Chaprnonin_Cpn10_CS.
 IPR011032; GroES-like. 

Pfam

 PF00166; Cpn10 

SMART

 SM00883; Cpn10 

PROSITE

 PS00681; CHAPERONINS_CPN10 

PRINTS

 PR00297; CHAPERONIN10.