CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000832
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Exocyst complex component 8 
Protein Synonyms/Alias
 Exocyst complex 84 kDa subunit 
Gene Name
 Exoc8 
Gene Synonyms/Alias
 Exo84 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
693EGVGKPAKQLQDLRNacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. 
Sequence Annotation
 DOMAIN 173 273 PH.
 MOD_RES 313 313 Phosphothreonine (By similarity).  
Keyword
 3D-structure; Cell projection; Complete proteome; Cytoplasm; Direct protein sequencing; Exocytosis; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 716 AA 
Protein Sequence
MSDSGASRLR RQLESGGFEA RLYVKQLSQQ SDGDRDLQEH RQRVQALAEE TAQNLKRNVY 60
QNYRQFIETA REISYLESEM YQLSHLLTEQ KSSLESIPLA LLPAAAAGAS TGEDTAGAGP 120
RERGAAQAGF LPGPAGVPRE GPGTGEEGKQ RTLTTLLEKV EGCRDLLETP GQYLVYNGDL 180
VEYEADHMAQ LQRVHGFLMN DCLLVATWLP QRRGMYRYNA LYPLDRLAVV NVKDNPPMKD 240
MFKLLMFPES RIFQAENAKI KREWLEVLEE TKRALSDKRR REQEEAAALR APPPVTSKGS 300
NPFEDEAEEE LATPEAEEEK VDLSMEWIQE LPEDLDVCIA QRDFEGAVDL LDKLNHYLED 360
KPSPPSVKEL RAKVDERVRQ LTEVLVFELS PDRSLRGGPK ATRRAVSQLI RLGQCTKACE 420
LFLRNRAAAV HTAIRQLRIE GATLLYIHKL CHVFFTSLLE TAREFETDFA GTDSGCYSAF 480
VVWARSAMGM FVDAFSKQVF DSKESLSTAA ECVKVAKEHC QQLGEIGLDL TFIIHALLVK 540
DIQGALLSYK EIIIEATKHR NSEEMWRRMN LMTPEALGKL KEEMRSCGVS NFEQYTGDDC 600
WVNLSYTVVA FTKQTMGFLE EALKLYFPEL HMVLLESLVE VILVAVQHVD YSLRCEQDPE 660
KKTFIRQNAS FLYDTVLPVV ERRFEEGVGK PAKQLQDLRN ASRLLRVNPE STTSVV 716 
Gene Ontology
 GO:0000145; C:exocyst; IDA:RGD.
 GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0034613; P:cellular protein localization; IMP:RGD.
 GO:0006887; P:exocytosis; TAS:RGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR016159; Cullin_repeat-like_dom.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR014812; Vps51. 
Pfam
 PF08700; Vps51 
SMART
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN 
PRINTS