UniProt Accession

 H1BP3_MOUSE; Q3TC93; E9QLQ4; Q9Z1K1 

Genbank Protein ID

 AJ132192; AK170838; AC122860 

Genbank Nucleotide ID

 CAA10600.1; BAE42064.1 

Protein Name

 HCLS1-binding protein 3 

Protein Synonyms/Alias

 HS1-binding protein 3; HSP1BP-3 

Gene Name

 Hs1bp3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
96	SLPPLPRKVLFVGES	ubiquitination	[1]
335	PKPQTKPKPLVPAKP	acetylation	[2]
335	PKPQTKPKPLVPAKP	succinylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

 May be a modulator of IL-2 signaling. 

Sequence Annotation

 DOMAIN 19 142 PX.
 MOD_RES 1 1 N-acetylmethionine (By similarity).
 MOD_RES 3 3 Phosphoserine (By similarity).
 MOD_RES 191 191 Phosphoserine (By similarity).
 MOD_RES 341 341 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 395 AA 

Protein Sequence

Gene Ontology

 GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
 GO:0007166; P:cell surface receptor signaling pathway; TAS:MGI.
 GO:0030217; P:T cell differentiation; TAS:MGI. 

Interpro

 IPR001683; Phox. 

Pfam

 PF00787; PX 

SMART

 SM00312; PX 

PROSITE

 PS50195; PX 

PRINTS